The rarity of efficient tools with spatiotemporal resolution and biocompatibility capabilities
remains a major challenge for further progress and application of signaling manipulation …

Nitric oxide (NO) represents a crucial mediator to regulate cerebral blood flow (CBF) in the
human brain both under basal conditions and in response to somatosensory stimulation. An …

The ability to detect, process, and react to light, sound, temperature, pressure, 34 and other
environmental signals is a necessary and defining characteristic of life. 35 Elucidating the …

Transient receptor potential ankyrin 1 (TRPA1) is a polymodal nonselective cation channel
sensitive to different physical and chemical stimuli. TRPA1 is associated with many …

The transient receptor potential (TRP) cation channel superfamily comprises more than 50
channels that play crucial roles in physiological processes. TRP channels are responsive to …

Introduction TRPA1 is a non-selective cation channel predominantly expressed in sensory
neurons, and functions as an irritant sensor for a plethora of noxious external stimuli and …

Metastasis is the hallmark of failed tumor treatment and is typically associated with death
due to cancer. Transient receptor potential (TRP) channels affect changes in intracellular …

Allergic asthma is a common chronic inflammation of the airways and causes airway
remodeling eventually. For a long time, investigators have been focusing on the …

The role of mammalian Transient Receptor Potential Ankyrin 1 (TRPA1) as a
mechanosensor is controversial. Here, we report that purified human TRPA1 (hTRPA1) with …

Transient receptor potential (TRP) channels are a superfamily of cation transmembrane
proteins that are expressed in many tissues and respond to many sensory stimuli. TRP …