Heart disease and stroke statistics—2023 update: a report from the American Heart Association

CW Tsao, AW Aday, ZI Almarzooq, CAM Anderson… - Circulation, 2023 - Am Heart Assoc
Background: The American Heart Association, in conjunction with the National Institutes of
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …

2024 heart disease and stroke statistics: a report of US and global data from the American Heart Association

SS Martin, AW Aday, ZI Almarzooq, CAM Anderson… - Circulation, 2024 - Am Heart Assoc
BACKGROUND: The American Heart Association (AHA), in conjunction with the National
Institutes of Health, annually reports the most up-to-date statistics related to heart disease …

Validation of biomarkers of aging

M Moqri, C Herzog, JR Poganik, K Ying, JN Justice… - Nature medicine, 2024 - nature.com
The search for biomarkers that quantify biological aging (particularly 'omic'-based
biomarkers) has intensified in recent years. Such biomarkers could predict aging-related …

Distinguishing between driver and passenger mechanisms of aging

JP de Magalhães - Nature Genetics, 2024 - nature.com
Understanding why we age is a long-standing question, and many mechanistic theories of
aging have been proposed. Owing to limitations in studying the aging process, including a …

Telomere length and the risk of cardiovascular diseases: A Mendelian randomization study

Y Deng, Q Li, F Zhou, G Li, J Liu, J Lv, L Li… - Frontiers in …, 2022 - frontiersin.org
Background The causal direction and magnitude of the associations between telomere
length (TL) and cardiovascular diseases (CVDs) remain uncertain due to susceptibility of …

[HTML][HTML] Sex/gender-related differences in inflammaging

F Olivieri, F Marchegiani, G Matacchione… - Mechanisms of ageing …, 2023 - Elsevier
Geroscience puts mechanisms of aging as a driver of the most common age-related
diseases and dysfunctions. Under this perspective, addressing the basic mechanisms of …

The association between telomere length and non-alcoholic fatty liver disease: a prospective study

L Tang, D Li, Y Ma, F Cui, J Wang, Y Tian - BMC medicine, 2023 - Springer
Background Research on the association between telomere length (TL) and incident non-
alcoholic fatty liver disease (NAFLD) is limited. This study examined this association and …

[HTML][HTML] Carcinogenesis induced by space radiation: A systematic review

Z Guo, G Zhou, W Hu - Neoplasia, 2022 - Elsevier
The carcinogenic risk from space radiation has always been a health risk issue of great
concern during space exploration. In recent years, a large number of cellular and animal …

Effects of putative metformin targets on phenotypic age and leukocyte telomere length: a mendelian randomisation study using data from the UK Biobank

S Luo, ICK Wong, CSL Chui, J Zheng… - The Lancet Healthy …, 2023 - thelancet.com
Background Metformin, a first-line medication for type 2 diabetes, might also have a
protective effect against ageing-related diseases, but so far little experimental evidence is …

Telomere length changes in cancer: insights on carcinogenesis and potential for non-invasive diagnostic strategies

Z Holesova, L Krasnicanova, R Saade, O Pös, J Budis… - Genes, 2023 - mdpi.com
Telomere dynamics play a crucial role in the maintenance of chromosome integrity; changes
in telomere length may thus contribute to the development of various diseases including …