The therapeutic potential of non-invasive and invasive cerebellar stimulation techniques in hereditary ataxias
The degenerative ataxias comprise a heterogeneous group of inherited and acquired
disorders that are characterized by a progressive cerebellar syndrome, frequently in …
disorders that are characterized by a progressive cerebellar syndrome, frequently in …
[HTML][HTML] Cerebellar deep brain stimulation for movement disorders
CH Tai, SH Tseng - Neurobiology of Disease, 2022 - Elsevier
Deep brain stimulation (DBS) conventionally target at basal ganglia or thalamic structures,
modulating nodal points in the cortico-basal ganglia circuit, in order to effectively treat …
modulating nodal points in the cortico-basal ganglia circuit, in order to effectively treat …
Neuromodulation of the cerebellum rescues movement in a mouse model of ataxia
LN Miterko, T Lin, J Zhou, ME van der Heijden… - Nature …, 2021 - nature.com
Deep brain stimulation (DBS) relieves motor dysfunction in Parkinson's disease, and other
movement disorders. Here, we demonstrate the potential benefits of DBS in a model of …
movement disorders. Here, we demonstrate the potential benefits of DBS in a model of …
Purkinje cell misfiring generates high-amplitude action tremors that are corrected by cerebellar deep brain stimulation
AM Brown, JJ White, ME van der Heijden, J Zhou, T Lin… - Elife, 2020 - elifesciences.org
Tremor is currently ranked as the most common movement disorder. The brain regions and
neural signals that initiate the debilitating shakiness of different body parts remain unclear …
neural signals that initiate the debilitating shakiness of different body parts remain unclear …
Advances in DBS technology and novel applications: focus on movement disorders
Abstract Purpose of Review Deep brain stimulation (DBS) is an established treatment in
several movement disorders, including Parkinson's disease, dystonia, tremor, and Tourette …
several movement disorders, including Parkinson's disease, dystonia, tremor, and Tourette …
Safety and outcomes of dentate nucleus deep brain stimulation for cerebellar ataxia
Cerebellar symptoms remain orphan of treatment options despite being prevalent and
incapacitating. Investigate whether dentate nucleus deep brain stimulation (DN DBS) is safe …
incapacitating. Investigate whether dentate nucleus deep brain stimulation (DN DBS) is safe …
[HTML][HTML] Molecular mechanisms and therapeutics for spinocerebellar ataxia type 2
PA Egorova, IB Bezprozvanny - Neurotherapeutics, 2019 - Elsevier
The effective therapeutic treatment and the disease-modifying therapy for spinocerebellar
ataxia type 2 (SCA2)(a progressive hereditary disease caused by an expansion of …
ataxia type 2 (SCA2)(a progressive hereditary disease caused by an expansion of …
A review of neurophysiological effects and efficiency of waveform parameters in deep brain stimulation
Neurostimulation has diverse clinical applications and potential as a treatment for medically
refractory movement disorders, epilepsy, and other neurological disorders. However, the …
refractory movement disorders, epilepsy, and other neurological disorders. However, the …
[HTML][HTML] A novel naïve Bayes approach to identifying grooming behaviors in the force-plate actometric platform
CJ Anderson, R Cadeddu, DN Anderson… - Journal of Neuroscience …, 2024 - Elsevier
Background Self-grooming behavior in rodents serves as a valuable behavioral index for
investigating stereotyped and perseverative responses. Most current grooming analyses rely …
investigating stereotyped and perseverative responses. Most current grooming analyses rely …
Investigation of neuromodulatory effect of anodal cerebellar transcranial direct current stimulation on the primary motor cortex using functional near-infrared …
Cerebellar brain inhibition (CBI), a neural connection between the cerebellum and primary
motor cortex (M1), has been researched as a target pathway for neuromodulation to improve …
motor cortex (M1), has been researched as a target pathway for neuromodulation to improve …