The gut microbiota represents a 'metabolic organ'that can regulate human metabolism. Intact
gut microbiota contributes to host homeostasis, whereas compositional perturbations …

Sarcopenia has been defined as a progressive decline of skeletal muscle mass, strength,
and functions in elderly people. It is accompanied by physical frailty, functional disability …

Sarcopenia is an important public health problem, characterized by age-related loss of
muscle mass and muscle function. It is a precursor of physical frailty, mobility limitation, and …

Intensive care unit-acquired weakness (ICUAW) occurs in critically ill patients stemming from
the critical illness itself, and results in sustained disability long after the ICU stay. Weakness …

Aging is a complex process characterized by progressive multisystem derangement
predisposing individuals to increased risk of developing negative health outcomes …

Background Skeletal muscle atrophy is defined as a reduction of muscle mass caused by
excessive protein degradation. However, the development of therapeutic interventions is still …

Aging skeletal muscles are characterized by a progressive decline in muscle mass and
muscular strength. Such muscular dysfunctions are usually associated with structural and …

Muscle wasting, known as cachexia, is a debilitating condition associated with chronic
inflammation such as during cancer. Beneficial microbes have been shown to optimize …

Sarcopenia, the age-related loss of skeletal muscle mass and function, affects 5–13% of
individuals aged over 60 years. While rodents are widely-used model organisms, which …

Two-dimensional (2D) cell cultures do not reflect the in vivo situation, and thus it is important
to develop predictive three-dimensional (3D) in vitro models with enhanced reliability and …