A guide to studying mitochondria transfer

S Tiash, JR Brestoff, C Crewe - Nature Cell Biology, 2023 - nature.com
Mitochondria can shuttle between adjacent cells or travel to distant organs by breaking away
from the parent cell and entering the circulation. Here, we briefly review the state of research …

Clinical Chemotherapeutic Agent Coordinated Copper‐Based Nanoadjuvants for Efficiently Sensitizing Cancer Chemo‐Immunotherapy by Cuproptosis‐Mediated …

H Tian, J Duan, B Li, S Qin, EC Nice… - Advanced Functional …, 2023 - Wiley Online Library
Chemo‐immunotherapy has shown great success in boosting systemic anti‐tumor effects in
the clinic. However, cancer cells can escape the maximum impact of chemotherapy through …

Extracellular vesicle-mediated interorgan communication in metabolic diseases

S Hu, Y Hu, W Yan - Trends in Endocrinology & Metabolism, 2023 - cell.com
The body partially maintains metabolic homeostasis through interorgan communication
between metabolic organs under physiological conditions. This crosstalk is known to be …

Transferred mitochondria accumulate reactive oxygen species, promoting proliferation

CU Kidwell, JR Casalini, S Pradeep, SD Scherer… - Elife, 2023 - elifesciences.org
Recent studies reveal that lateral mitochondrial transfer, the movement of mitochondria from
one cell to another, can affect cellular and tissue homeostasis. Most of what we know about …

Metabolic landscape in cardiac aging: insights into molecular biology and therapeutic implications

S Xie, SC Xu, W Deng, Q Tang - Signal transduction and targeted …, 2023 - nature.com
Cardiac aging is evident by a reduction in function which subsequently contributes to heart
failure. The metabolic microenvironment has been identified as a hallmark of malignancy …

Muscle mitochondrial transplantation can rescue and maintain cellular homeostasis

D Bhattacharya, MB Slavin… - American Journal of …, 2023 - journals.physiology.org
Mitochondria control cellular functions through their metabolic role. Recent research that has
gained considerable attention is their ability to transfer between cells. This has the potential …

An estimate of extracellular vesicle secretion rates of human blood cells

M Auber, P Svenningsen - Journal of Extracellular Biology, 2022 - Wiley Online Library
Extracellular vesicles (EVs) have been implicated in the intercellular transfer of RNA and
proteins through cellular secretion into the extracellular space. In blood plasma, circulating …

Mitochondrial regulation and white adipose tissue homeostasis

Q Zhu, YA An, PE Scherer - Trends in cell biology, 2022 - cell.com
The important role of mitochondria in the regulation of white adipose tissue (WAT)
remodeling and energy balance is increasingly appreciated. The remarkable heterogeneity …

Cardiac macrophage metabolism in health and disease

BJ Kopecky, KJ Lavine - Trends in Endocrinology & Metabolism, 2024 - cell.com
Cardiac macrophages are essential mediators of cardiac development, tissue homeostasis,
and response to injury. Cell-intrinsic shifts in metabolism and availability of metabolites …

Multifaceted mitochondrial quality control in brown adipose tissue

K Aquilano, B Zhou, JR Brestoff, D Lettieri-Barbato - Trends in Cell Biology, 2023 - cell.com
Brown adipose tissue (BAT) controls mammalian core body temperature by non-shivering
thermogenesis. BAT is extraordinarily rich in mitochondria, which have the peculiarity of …