Bacterial chromosomes are folded to compact DNA and facilitate cellular processes.
Studying model bacteria has revealed aspects of chromosome folding that are applicable to …

The histone-like nucleoid structuring (H-NS) protein is a major component of the folded
chromosome in Escherichia coli and related bacteria. Functions attributed to H-NS include …

Widespread intragenic transcription initiation has been observed in many species. Here we
show that the Escherichia coli ehxCABD operon contains numerous intragenic promoters in …

The multiple antibiotic resistance (mar) operon of Escherichia coli is a paradigm for
chromosomally encoded antibiotic resistance in enteric bacteria. The locus is recognised for …

Decades of research have probed the interplay between chromatin (genomic DNA
associated with proteins and RNAs) and transcription by RNA polymerase (RNAP) in all …

Nucleoid‐associated proteins (NAPs) are architectural proteins of the bacterial chromosome
and transcription factors that dynamically organise the chromosome and regulate gene …

Horizontal gene transfer permits rapid dissemination of genetic elements between
individuals in bacterial populations. Transmitted DNA sequences may encode favourable …

Pf filamentous prophages are prevalent among clinical and environmental Pseudomonas
aeruginosa isolates. Pf4 and Pf5 prophages are integrated into the host genomes of PAO1 …

Highlights•Similarities in the DNA binding properties of H-NS and RNA polymerase.•
Interactions between H-NS and RNA polymerase throughout the transcription cycle.•H-NS …

Dps is a multifunctional homododecameric protein that oxidizes Fe2+ ions accumulating
them in the form of Fe2O3 within its protein cavity, interacts with DNA tightly condensing …