[PDF][PDF] Nasal drug delivery system-an overview

M Alagusundaram, B Chengaiah… - Int J Res Pharm …, 2010 - researchgate.net
The use of the nasal route for the delivery of challenging drugs such as small polar
molecules, vaccines, hormones, peptides and proteins has created much interest in …

A quantitative approach to predicting lung deposition profiles of pharmaceutical powder aerosols

S Yaqoubi, HK Chan, A Nokhodchi… - International Journal of …, 2021 - Elsevier
Dry powder inhalers (DPI) are widely used systems for pulmonary delivery of therapeutics.
The inhalation performance of DPIs is influenced by formulation features, inhaler device and …

Intranasal drug delivery system-A glimpse to become maestro

S Upadhyay, A Parikh, P Joshi… - Journal of applied …, 2011 - japsonline.com
Intranasal drug delivery–which has been practiced for thousands of years, has been given a
new lease of life. It is a useful delivery method for drugs that are active in low doses and …

Co-electrospraying technology as a novel approach for dry powder inhalation formulation of montelukast and budesonide for pulmonary co-delivery

S Yaqoubi, K Adibkia, A Nokhodchi, S Emami… - International Journal of …, 2020 - Elsevier
In the current study electrospraying methodology was used for particle engineering of
montelukast and budesonide to prepare a combined inhalable dry powder formulation …

Flow and particle deposition in the Turbuhaler: A CFD simulation

J Milenkovic, AH Alexopoulos, C Kiparissides - International journal of …, 2013 - Elsevier
In this work the steady-state flow in a commercial dry powder inhaler device, DPI (ie,
Turbuhaler) is described using computational fluid dynamics. The Navier–Stokes equations …

Low-dose capsule filling of inhalation products: Critical material attributes and process parameters

E Faulhammer, M Fink, M Llusa, SM Lawrence… - International journal of …, 2014 - Elsevier
The aim of the present work was to identify the material attributes and process parameters of
a dosator-nozzle capsule filling machine that are critical in low-fill weight capsule filling for …

The role of lactose carrier on the powder behavior and aerodynamic performance of bosentan microparticles for dry powder inhalation

HJ Lee, HG Lee, YB Kwon, JY Kim, YS Rhee… - European Journal of …, 2018 - Elsevier
In this study, we prepared carrier-based formulations for dry powder inhalers by mixing
bosentan microparticles with carrier, prepared in three separate types of lactose. Spray …

Carrier-based dry powder inhalation: Impact of carrier modification on capsule filling processability and in vitro aerodynamic performance

E Faulhammer, V Wahl, S Zellnitz, JG Khinast… - International journal of …, 2015 - Elsevier
This study aims to investigate the effect of carrier characteristics and dosator capsule filling
operation on the in vitro deposition of mixtures containing salbutamol sulphate (SS) and …

Spray dried tigecycline dry powder aerosols for the treatment of nontuberculous mycobacterial pulmonary infections

SE Maloney, IM Alshiraihi, A Singh, IE Stewart… - Tuberculosis, 2023 - Elsevier
Nontuberculous mycobacterial (NTM) pulmonary infections are a global health concern and
a significant contributor to lung disease. Systemic therapies of a cocktail of antibiotics …

Deposition and fine particle production during dynamic flow in a dry powder inhaler: a CFD approach

J Milenkovic, AH Alexopoulos, C Kiparissides - International journal of …, 2014 - Elsevier
In this work the dynamic flow as well as the particle motion and deposition in a commercial
dry powder inhaler, DPI (ie, Turbuhaler) is described using computational fluid dynamics …