Modeling immunity in microphysiological systems
BJ Kwee, X Li, XX Nguyen… - Experimental …, 2023 - journals.sagepub.com
There is a need for better predictive models of the human immune system to evaluate safety
and efficacy of immunomodulatory drugs and biologics for successful product development …
and efficacy of immunomodulatory drugs and biologics for successful product development …
Boesenbergia rotunda and Its Pinostrobin for Atopic Dermatitis: Dual 5-Lipoxygenase and Cyclooxygenase-2 Inhibitor and Its Mechanistic Study through Steady-State …
D Liana, C Eurtivong, A Phanumartwiwath - Antioxidants, 2024 - mdpi.com
Human 5-lipoxygenase (5-LOX) and cyclooxygenase-2 (COX-2) are potential targets for
suppressing pruritic skin inflammation in atopic dermatitis (AD). In addition, Staphylococcus …
suppressing pruritic skin inflammation in atopic dermatitis (AD). In addition, Staphylococcus …
Macrocystis pyrifera Lipids Reduce Cytokine-Induced Pro-Inflammatory Signalling and Barrier Dysfunction in Human Keratinocyte Models
Atopic dermatitis is a chronic condition where epidermal barrier dysfunction and cytokine
production by infiltrating immune cells exacerbate skin inflammation and damage. A total …
production by infiltrating immune cells exacerbate skin inflammation and damage. A total …
Cytotoxic and Immunomodulatory Effects of Hypericin as a Photosensitizer in Photodynamic Therapy Used on Skin Cell Cultures
Determination of the hypericin–photodynamic (HY–PDT) effect on the secretion of cytokines
secreted by the skin cells, may be the basis for using the immunomodulatory effect of …
secreted by the skin cells, may be the basis for using the immunomodulatory effect of …
A Platform for Testing the Biocompatibility of Implants: Silicone Induces a Proinflammatory Response in a 3D Skin Equivalent
R Nuwayhid, T Schulz, F Siemers, J Schreiter, P Kobbe… - Biomedicines, 2024 - mdpi.com
Biocompatibility testing of materials is carried out in 2D cell cultures or animal models
despite serious limitations. 3D skin equivalents are advanced in vitro models for human skin …
despite serious limitations. 3D skin equivalents are advanced in vitro models for human skin …
Incorporating NK Cells in a Three-Dimensional Organotypic Culture System for Human Skin Stem Cells: Modeling Skin Diseases and Immune Cell Interplay
B Arjmand, SK Hamidpour, A Tayanloo-Beik… - 2023 - Springer
Natural killer (NK) cells are a part of a sophisticated immune system that is necessary for the
skin because it is a crucial organ that is continually exposed to environmental influences …
skin because it is a crucial organ that is continually exposed to environmental influences …
Adipokines-enriched adipose extract restores skin barrier and ameliorates inflammatory dysregulation in an atopic dermatitis mouse model
J Guan, J Feng, M Xu, M Liu, Y He… - Plastic and Reconstructive …, 2021 - journals.lww.com
Background: Atopic dermatitis (AD) is a chronic dermatosis with high incidence worldwide
characterized by skin barrier abnormalities and immune dysregulation. Conventional …
characterized by skin barrier abnormalities and immune dysregulation. Conventional …