Actin is a key regulator of RNA polymerase (pol) II transcription. In complex with specific
hnRNPs, it has been proposed that actin functions to recruit pol II coactivators during the …

Eukaryotic DNA is packaged into chromatin by histone proteins, which assemble the DNA
into an organized, higher-order structure. The precise organization of chromatin is essential …

Recent research has provided convincing evidence that actin plays several important roles
in gene transcription. First, actin can bind transcription factors and determine their …

The proteins actin and myosin have a firm place in the muscles, where they are responsible
for contraction. Although recent investigations have shown that they are found in the …

Expression of protein-coding genes in eukaryotes relies on the coordinated action of many
sophisticated molecular machineries. Transcription produces precursor mRNAs (pre …

Actin is not only a major cytoskeletal component in all eukaryotic cells but also a nuclear
protein that plays a role in gene transcription. We put together data from in vitro and in vivo …

Actin exists as a dynamic equilibrium of monomers and polymers within the nucleus of living
cells. It is utilized by the cell for many aspects of gene regulation, including mRNA …

Actin is a key player for nuclear structure and function regulating both chromosome
organization and gene activity. In the cell nucleus actin interacts with many different proteins …

Within the past two years, actin has been implicated in eukaryotic gene transcription by all
three classes of RNA polymerase. Moreover, within just the past year, actin has been …

Over the past few decades, actin's presence in the nucleus has been demonstrated. Actin is
a key protein necessary for different nuclear processes. Although actin is well known for its …