Brucella: a pathogen without classic virulence genes

MN Seleem, SM Boyle, N Sriranganathan - Veterinary microbiology, 2008 - Elsevier
The first species of Brucella was isolated and characterized almost 120 years ago and
recently the complete nucleotide sequences of the genomes of a number of well …

Development of a selective culture medium for primary isolation of the main Brucella species

MJ De Miguel, CM Marín, PM Muñoz… - Journal of clinical …, 2011 - Am Soc Microbiol
Bacteriological diagnosis of brucellosis is performed by culturing animal samples directly on
both Farrell medium (FM) and modified Thayer-Martin medium (mTM). However, despite …

Immune Response to Mucosal Brucella Infection

R López-Santiago, AB Sánchez-Argáez… - Frontiers in …, 2019 - frontiersin.org
Brucellosis is one of the most prevalent bacterial zoonosis of worldwide distribution. The
disease is caused by Brucella spp., facultative intracellular pathogens. Brucellosis in …

Brucella spp. of amphibians comprise genomically diverse motile strains competent for replication in macrophages and survival in mammalian hosts

S Al Dahouk, S Köhler, A Occhialini… - Scientific reports, 2017 - nature.com
Twenty-one small Gram-negative motile coccobacilli were isolated from 15 systemically
diseased African bullfrogs (Pyxicephalus edulis), and were initially identified as …

Isolation and expression of recombinant antibody fragments to the biological warfare pathogen Brucella melitensis

A Hayhurst, S Happe, R Mabry, Z Koch… - Journal of …, 2003 - Elsevier
Brucella melitensis is a highly infectious animal pathogen able to cause a recurring
debilitating disease in humans and is therefore high on the list of biological warfare agents …

Organelle robbery: Brucella interactions with the endoplasmic reticulum

J Celli, JP Gorvel - Current opinion in microbiology, 2004 - Elsevier
Brucella is an intracellular pathogen that survives and multiplies inside host macrophages to
cause brucellosis. The underlying mechanisms of intracellular survival, including the …

The regulon of Brucella abortus two-component system BvrR/BvrS reveals the coordination of metabolic pathways required for intracellular life

O Rivas-Solano, M Van der Henst, A Castillo-Zeledón… - PLoS …, 2022 - journals.plos.org
Brucella abortus is a facultative intracellular pathogen causing a severe zoonotic disease
worldwide. The two-component regulatory system (TCS) BvrR/BvrS of B. abortus is …

Genome Degradation in Brucella ovis Corresponds with Narrowing of Its Host Range and Tissue Tropism

RM Tsolis, R Seshadri, RL Santos, FJ Sangari… - PloS one, 2009 - journals.plos.org
Brucella ovis is a veterinary pathogen associated with epididymitis in sheep. Despite its
genetic similarity to the zoonotic pathogens B. abortus, B. melitensis and B. suis, B. ovis …

The role of neutrophils in brucellosis

E Moreno, E Barquero-Calvo - Microbiology and Molecular …, 2020 - Am Soc Microbiol
Brucellosis is a bacterial disease of domestic animals and humans. The pathogenic ability of
Brucella organisms relies on their stealthy strategy and their capacity to replicate within host …

Adaptation of the Brucellae to their intracellular niche

RM Roop, BH Bellaire, MW Valderas… - Molecular …, 2004 - Wiley Online Library
Members of the bacterial genus Brucella are facultative intracellular pathogens that reside
predominantly within membrane‐bound compartments within two host cell types …