[HTML][HTML] Lycopene: a natural arsenal in the war against oxidative stress and cardiovascular diseases

MN Bin-Jumah, MS Nadeem, SJ Gilani, B Mubeen… - Antioxidants, 2022 - mdpi.com
Lycopene is a bioactive red pigment found in plants, especially in red fruits and vegetables,
including tomato, pink guava, papaya, pink grapefruit, and watermelon. Several research …

The NLRP3 inflammasome and the emerging role of colchicine to inhibit atherosclerosis-associated inflammation

GJ Martinez, DS Celermajer, S Patel - Atherosclerosis, 2018 - Elsevier
Atherosclerosis is considered a chronic inflammatory disease of the arterial wall. Recently,
compelling evidence has arisen for the role of monocytes and neutrophils and a particular …

Single-cell immune landscape of human atherosclerotic plaques

DM Fernandez, AH Rahman, NF Fernandez… - Nature medicine, 2019 - nature.com
Atherosclerosis is driven by multifaceted contributions of the immune system within the
circulation and at vascular focal sites. However, specific characteristics of dysregulated …

Systemic immune‐inflammation index (SII) predicted clinical outcome in patients with coronary artery disease

YL Yang, CH Wu, PF Hsu, SC Chen… - European journal of …, 2020 - Wiley Online Library
Background This study examines the predictive value of a novel systemic immune‐
inflammation index (SII, platelet× neutrophil/lymphocyte ratio) in coronary artery disease …

The associations of two novel inflammation indexes, SII and SIRI with the risks for cardiovascular diseases and all-cause mortality: a ten-year follow-up study in 85,154 …

Z Jin, Q Wu, S Chen, J Gao, X Li, X Zhang… - Journal of …, 2021 - Taylor & Francis
Background: SII and SIRI are two novel systemic inflammation indexes that were suggested
in predicting poor outcomes in cancers. However, no studies have examined their effect on …

Inflamed moods: a review of the interactions between inflammation and mood disorders

JD Rosenblat, DS Cha, RB Mansur… - Progress in Neuro …, 2014 - Elsevier
Mood disorders have been recognized by the World Health Organization (WHO) as the
leading cause of disability worldwide. Notwithstanding the established efficacy of …

Anti-inflammatory therapies for cardiovascular disease

PM Ridker, TF Lüscher - European heart journal, 2014 - academic.oup.com
Atherothrombosis is no longer considered solely a disorder of lipoprotein accumulation in
the arterial wall. Rather, the initiation and progression of atherosclerotic lesions is currently …

DNA methyltransferase 3 alpha and TET methylcytosine dioxygenase 2 restrain mitochondrial DNA-mediated interferon signaling in macrophages

I Cobo, TN Tanaka, KC Mangalhara, A Lana, C Yeang… - Immunity, 2022 - cell.com
Deleterious somatic mutations in DNA methyltransferase 3 alpha (DNMT3A) and TET
mehtylcytosine dioxygenase 2 (TET2) are associated with clonal expansion of …

Vascular macrophages in atherosclerosis

H Xu, J Jiang, W Chen, W Li… - Journal of immunology …, 2019 - Wiley Online Library
Atherosclerosis is the main pathological basis for the occurrence of most cardiovascular
diseases, the leading global health threat, and a great burden for society. It has been well …

[HTML][HTML] A multi-use deep learning method for CITE-seq and single-cell RNA-seq data integration with cell surface protein prediction and imputation

J Lakkis, A Schroeder, K Su, MYY Lee… - Nature machine …, 2022 - nature.com
CITE-seq, a single-cell multi-omics technology that measures RNA and protein expression
simultaneously in single cells, has been widely applied in biomedical research, especially in …