5-Ene-4-thiazolidinones–An efficient tool in medicinal chemistry
The presented review is an attempt to summarize a huge volume of data on 5-ene-4-
thiazolidinones being a widely studied class of small molecules used in modern organic and …
thiazolidinones being a widely studied class of small molecules used in modern organic and …
Piperazine scaffold: A remarkable tool in generation of diverse pharmacological agents
M Shaquiquzzaman, G Verma, A Marella… - European journal of …, 2015 - Elsevier
Piperazine is one of the most sought heterocyclics for the development of new drug
candidates. This ring can be traced in a number of well established, commercially available …
candidates. This ring can be traced in a number of well established, commercially available …
Cytotoxic effect, enzyme inhibition, and in silico studies of some novel N-substituted sulfonyl amides incorporating 1,3,4-oxadiazol structural motif
The acetylcholinesterase and carbonic anhydrase inhibitors (AChEIs and h CAIs) remain
key therapeutic agents for many bioactivities such as anti-Alzheimer and antiobesity …
key therapeutic agents for many bioactivities such as anti-Alzheimer and antiobesity …
Multi-target compounds acting in cancer progression: Focus on thiosemicarbazone, thiazole and thiazolidinone analogues
LRP de Siqueira, PAT de Moraes Gomes… - European Journal of …, 2019 - Elsevier
Currently, cancer and its progression to metastasis result in a large number of deaths. The
lack of new drugs, appropriate clinical trials for metastasis preventive drugs and incomplete …
lack of new drugs, appropriate clinical trials for metastasis preventive drugs and incomplete …
A conceptual review of rhodanine: current applications of antiviral drugs, anticancer and antimicrobial activities
Rhodanines are accepted as advantaged heterocycles in medicinal chemistry as one of the
4-thiazolidinones subtypes. The aim of this paper is to analyze the features of rhodanine and …
4-thiazolidinones subtypes. The aim of this paper is to analyze the features of rhodanine and …
In vitro and in silico studies of fluorinated 2, 3‐disubstituted thiazolidinone‐pyrazoles as potential α‐amylase inhibitors and antioxidant agents
As part of our effort to identify potent α‐amylase inhibitors, in the present study, a novel
series of fluorinated thiazolidinone‐pyrazole hybrid molecules were prepared by the …
series of fluorinated thiazolidinone‐pyrazole hybrid molecules were prepared by the …
Recent developments with rhodanine as a scaffold for drug discovery
D Kaminskyy, A Kryshchyshyn… - Expert Opinion on Drug …, 2017 - Taylor & Francis
Introduction: Rhodanines, as one of the 4-thiazolidinones subtypes, are recognized as
privileged heterocycles in medicinal chemistry. The main achievements include the …
privileged heterocycles in medicinal chemistry. The main achievements include the …
New progress in azole compounds as antimicrobial agents
HZ Zhang, LL Gan, H Wang… - Mini reviews in medicinal …, 2017 - ingentaconnect.com
The increasing incidence of microbial resistance and newly emerging pathogens have
become a serious challenge for public health. More and more efforts have been directed to …
become a serious challenge for public health. More and more efforts have been directed to …
Antitubercular properties of thiazolidin-4-ones–A review
N Trotsko - European Journal of Medicinal Chemistry, 2021 - Elsevier
Thiazolidin-4-one scaffold has great potential for medicinal chemistry and is of interest to
scientists in view of wide spectrum of biological activity. This scaffold is often used for …
scientists in view of wide spectrum of biological activity. This scaffold is often used for …
An efficient ultrasound-assisted CH3COONa catalyzed synthesis of thiazolidinone molecule: theoretical and nonlinear optical evaluations of thiazolidinone-Schiff base …
Chemical synthesis, structural analysis, theoretical calculations and optical properties
exploration of (E)-2-((E)-(4-nitrobenzylidene) hydrazono)-3-phenyl-4-thiazolidinone 7 (C 16 …
exploration of (E)-2-((E)-(4-nitrobenzylidene) hydrazono)-3-phenyl-4-thiazolidinone 7 (C 16 …