Osteoarthritis: pathogenic signaling pathways and therapeutic targets
Osteoarthritis (OA) is a chronic degenerative joint disorder that leads to disability and affects
more than 500 million population worldwide. OA was believed to be caused by the wearing …
more than 500 million population worldwide. OA was believed to be caused by the wearing …
The cytokine network involved in the host immune response to periodontitis
W Pan, Q Wang, Q Chen - International journal of oral science, 2019 - nature.com
Periodontitis is an inflammatory disease involving the destruction of both soft and hard tissue
in the periodontal region. Although dysbiosis of the local microbial community initiates local …
in the periodontal region. Although dysbiosis of the local microbial community initiates local …
NF-κB signaling pathways in osteoarthritic cartilage destruction
MC Choi, J Jo, J Park, HK Kang, Y Park - Cells, 2019 - mdpi.com
Osteoarthritis (OA) is a type of joint disease associated with wear and tear, inflammation,
and aging. Mechanical stress along with synovial inflammation promotes the degradation of …
and aging. Mechanical stress along with synovial inflammation promotes the degradation of …
Signaling via the NFκB system
The nuclear factor kappa B (NFκB) family of transcription factors is a key regulator of immune
development, immune responses, inflammation, and cancer. The NFκB signaling system …
development, immune responses, inflammation, and cancer. The NFκB signaling system …
Apigenin in cancer therapy: Anti-cancer effects and mechanisms of action
X Yan, M Qi, P Li, Y Zhan, H Shao - Cell & bioscience, 2017 - Springer
Apigenin is a common dietary flavonoid that is abundantly present in many fruits, vegetables
and Chinese medicinal herbs and serves multiple physiological functions, such as strong …
and Chinese medicinal herbs and serves multiple physiological functions, such as strong …
[HTML][HTML] Health relevance of the modification of low grade inflammation in ageing (inflammageing) and the role of nutrition
Ageing of the global population has become a public health concern with an important socio-
economic dimension. Ageing is characterized by an increase in the concentration of …
economic dimension. Ageing is characterized by an increase in the concentration of …
Transcriptome profiling in swine macrophages infected with African swine fever virus at single-cell resolution
African swine fever virus (ASFV) is the causative agent of African swine fever, a highly
contagious and usually fatal disease in pigs. The pathogenesis of ASFV infection has not …
contagious and usually fatal disease in pigs. The pathogenesis of ASFV infection has not …
Regulation of tumour necrosis factor signalling: live or let die
Tumour necrosis factor (TNF) is a pro-inflammatory cytokine that has important roles in
mammalian immunity and cellular homeostasis. Deregulation of TNF receptor (TNFR) …
mammalian immunity and cellular homeostasis. Deregulation of TNF receptor (TNFR) …
[HTML][HTML] Invited review: Inflammation during the transition to lactation: New adventures with an old flame
For dairy cattle, the first several weeks of lactation represent the highest-risk period in their
lives after their own neonatal period. Although more than 50% of cows during this period are …
lives after their own neonatal period. Although more than 50% of cows during this period are …
Role of DJ-1 in the mechanism of pathogenesis of Parkinson's disease
LP Dolgacheva, AV Berezhnov, EI Fedotova… - Journal of Bioenergetics …, 2019 - Springer
DJ-1 protein has multiple specific mechanisms to protect dopaminergic neurons against
neurodegeneration in Parkinson's disease. Wild type DJ-1 can acts as oxidative stress …
neurodegeneration in Parkinson's disease. Wild type DJ-1 can acts as oxidative stress …