Microglia in neuroinflammation and neurodegeneration: from understanding to therapy

L Muzio, A Viotti, G Martino - Frontiers in neuroscience, 2021 - frontiersin.org
Microglia are the resident macrophages of the central nervous system (CNS) acting as the
first line of defense in the brain by phagocytosing harmful pathogens and cellular debris …

How does the immune system enter the brain?

JA Mapunda, H Tibar, W Regragui… - Frontiers in …, 2022 - frontiersin.org
Multiple Sclerosis (MS) is considered the most frequent inflammatory demyelinating disease
of the central nervous system (CNS). It occurs with a variable prevalence across the world. A …

Applications of deep learning techniques for automated multiple sclerosis detection using magnetic resonance imaging: A review

A Shoeibi, M Khodatars, M Jafari, P Moridian… - Computers in Biology …, 2021 - Elsevier
Multiple Sclerosis (MS) is a type of brain disease which causes visual, sensory, and motor
problems for people with a detrimental effect on the functioning of the nervous system. In …

The role of fecal microbiota transplantation in the treatment of neurodegenerative diseases: a review

JAT Matheson, RMD Holsinger - International Journal of Molecular …, 2023 - mdpi.com
Neurodegenerative diseases are highly prevalent but poorly understood, and with few
treatment options despite decades of intense research, attention has recently shifted toward …

Acetylcholinesterase inhibitors in the treatment of neurodegenerative diseases and the role of acetylcholinesterase in their pathogenesis

ŁJ Walczak-Nowicka, M Herbet - International journal of molecular …, 2021 - mdpi.com
Acetylcholinesterase (AChE) plays an important role in the pathogenesis of
neurodegenerative diseases by influencing the inflammatory response, apoptosis, oxidative …

Mercury involvement in neuronal damage and in neurodegenerative diseases

VL Cariccio, A Samà, P Bramanti, E Mazzon - Biological trace element …, 2019 - Springer
Neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease,
amyotrophic lateral sclerosis, and multiple sclerosis are characterized by a chronic and …

Different pieces of the same puzzle: a multifaceted perspective on the complex biological basis of Parkinson's disease

AC Müller-Nedebock, MCJ Dekker, MJ Farrer… - npj Parkinson's …, 2023 - nature.com
The biological basis of the neurodegenerative movement disorder, Parkinson's disease
(PD), is still unclear despite it being 'discovered'over 200 years ago in Western Medicine …

How does cognition relate to employment in multiple sclerosis? A systematic review

L Clemens, D Langdon - Multiple sclerosis and related disorders, 2018 - Elsevier
Background Almost half of people with multiple sclerosis (MS), with low levels of physical
disability, are unemployed. It is likely that the impact of “invisible” symptoms of MS, such as …

Multiple sclerosis: inflammatory and neuroglial aspects

G Papiri, G D'Andreamatteo, G Cacchiò, S Alia… - Current Issues in …, 2023 - mdpi.com
Multiple sclerosis (MS) represents the most common acquired demyelinating disorder of the
central nervous system (CNS). Its pathogenesis, in parallel with the well-established role of …

Worldwide prevalence of familial multiple sclerosis: A systematic review and meta-analysis

MH Harirchian, F Fatehi, P Sarraf, NM Honarvar… - Multiple sclerosis and …, 2018 - Elsevier
Background Several studies have suggested that the existence of a history of multiple
sclerosis (MS) in family, is one of the predisposing factors for MS. Based on our knowledge …