Coumarins belong to the benzopyrone family commonly found in many medicinal plants.
Natural coumarins demonstrated a wide spectrum of pharmacological activities, including …

Introduction and objectives To compare the long-term results of direct oral anticoagulants
(DOAC) vs vitamin K antagonists (VKA) in real-world-patients with nonvalvular atrial …

Introduction and objective Data from phase 2 clinical trials suggest that Factor XI inhibitors
may exhibit a more favorable efficacy/safety profile compared to current antithrombotic …

Introducción y objetivos Comparar los resultados a largo plazo de los anticoagulantes
orales directos (ACOD) frente a los antagonistas de la vitamina K (AVK) en pacientes del …

Background Oral anticoagulant therapy (VKA) is nowadays the mainstay of treatment in
primary and secondary stroke prevention in patients with atrial fibrillation. Given the limited …

Atrial fibrillation is a very common arrhythmia whose prevalence is expected to increase
significantly as the population ages. The associated stroke risk is a major cause of morbidity …

Antecedentes y objetivo La información proveniente de los ensayos clínicos fase 2 sugiere
que los inhibidores del factor XI podrían mostrar un perfil de eficacia/seguridad más …

During the last decade, non-vitamin K antagonist oral anticoagulants (NOACs)
revolutionized the thromboprophylaxis management of several medical conditions, including …

Background Real-world data from different regions are needed to support the external
validity of controlled trials and assess the impact of new oral anticoagulants (NOAC) in …

Introduction and objectives Vitamin K antagonists (VKAs) are still widely used for stroke
prevention in atrial fibrillation. However, the access to international normalised ratio (INR) …