[HTML][HTML] Mevalonate kinase-deficient THP-1 cells show a disease-characteristic pro-inflammatory phenotype
FA Politiek, M Turkenburg, R Ofman… - Frontiers in …, 2024 - frontiersin.org
Objective Bi-allelic pathogenic variants in the MVK gene, which encodes mevalonate kinase
(MK), an essential enzyme in isoprenoid biosynthesis, cause the autoinflammatory …
(MK), an essential enzyme in isoprenoid biosynthesis, cause the autoinflammatory …
[HTML][HTML] Molecular and cellular consequences of mevalonate kinase deficiency
FA Politiek, M Turkenburg, L Henneman… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Mevalonate kinase deficiency (MKD) is an autosomal recessive metabolic disorder
associated with recurrent autoinflammatory episodes. The disorder is caused by bi-allelic …
associated with recurrent autoinflammatory episodes. The disorder is caused by bi-allelic …