Distinct inflammation-related proteins associated with T cell immune recovery during chronic HIV-1 infection

LY Wan, HH Huang, C Zhen, SY Chen… - Emerging Microbes & …, 2023 - Taylor & Francis
Chronic inflammation and T cell dysregulation persist in individuals infected with human
immunodeficiency virus type 1 (HIV-1), even after successful antiretroviral treatment. The …

Abnormal blood microbiota profiles are associated with inflammation and immune restoration in HIV/AIDS individuals

X Guo, Z Wang, M Qu, Y Guo, M Yu, W Hong, C Zhang… - Msystems, 2023 - Am Soc Microbiol
Although gut microbiota alteration and related blood microbe profiles in human
immunodeficiency virus (HIV)-infected individuals are associated with the disease …

IP-10 Promotes Latent HIV Infection in Resting Memory CD4+ T Cells via LIMK-Cofilin Pathway

Z Wang, X Yin, M Ma, H Ge, B Lang, H Sun… - Frontiers in …, 2021 - frontiersin.org
A major barrier to HIV eradication is the persistence of viral reservoirs. Resting CD4+ T cells
are thought to be one of the major viral reservoirs, However, the underlying mechanism …

Transcriptome profiles of latently- and reactivated HIV-1 infected primary CD4+ T cells: A pooled data-analysis

A Inderbitzin, T Loosli, L Opitz, P Rusert… - Frontiers in …, 2022 - frontiersin.org
The main obstacle to cure HIV-1 is the latent reservoir. Antiretroviral therapy effectively
controls viral replication, however, it does not eradicate the latent reservoir. Latent CD4+ T …

Cannabinoid control of gingival immune activation in chronically SIV-infected rhesus macaques involves modulation of the indoleamine-2, 3-dioxygenase-1 pathway …

M McDew-White, E Lee, X Alvarez, K Sestak, BJ Ling… - …, 2022 - thelancet.com
Background HIV/SIV-associated periodontal disease (gingivitis/periodontitis)(PD) represents
a major comorbidity affecting people living with HIV (PLWH) on combination anti-retroviral …

Host immunity associated with spontaneous suppression of viremia in therapy-naïve young rhesus macaques following neonatal SHIV infection

TD Evangelous, M Berry, S Venkatayogi… - Journal of …, 2023 - Am Soc Microbiol
We recently found that a new pathogenic chimeric simian-human immunodeficiency virus
(SHIV) elicited heterologous human immunodeficiency virus type-1 (HIV-1) neutralizing …

[HTML][HTML] Targeted plasma proteomics reveals upregulation of distinct inflammatory pathways in people living with HIV

N Vadaq, L van de Wijer, LE van Eekeren, H Koenen… - Iscience, 2022 - cell.com
Despite antiretroviral therapy (ART), people living with HIV (PLHIV) display persistent
inflammation leading to non-AIDS-related co-morbidities. To better understand underlying …

Identification of novel candidate genes in rosacea by bioinformatic methods

Y Sun, LH Chen, YS Lu, HT Chu, Y Wu, XH Gao… - Cytokine, 2021 - Elsevier
Background Rosacea is a chronic inflammatory skin disease whose psychological
consequences severely affect patient's quality of life. Objective To identify candidate genes …

[HTML][HTML] Systems biology analysis reveals distinct molecular signatures associated with immune responsiveness to the BNT162b COVID-19 vaccine

I Odak, L Riemann, I Sandrock, A Cossmann… - …, 2024 - thelancet.com
Background Human immune responses to COVID-19 vaccines display a large heterogeneity
of induced immunity and the underlying immune mechanisms for this remain largely …

Distinct cytokine profiles in malaria coinfections: A systematic review

M Kotepui, W Mala, P Kwankaew… - PLOS Neglected …, 2023 - journals.plos.org
Background Few data exist on the distinct cytokine profiles of individuals with malaria
coinfections and other diseases. This study focuses on data collation of distinct cytokine …