[HTML][HTML] Emerging concepts of miRNA therapeutics: from cells to clinic
MicroRNAs (miRNAs) are very powerful genetic regulators, as evidenced by the fact that a
single miRNA can direct entire cellular pathways via interacting with a broad spectrum of …
single miRNA can direct entire cellular pathways via interacting with a broad spectrum of …
[HTML][HTML] Circular RNAs: new layer of complexity evading breast cancer heterogeneity
A Dawoud, ZI Zakaria, HH Rashwan… - Non-Coding RNA …, 2023 - Elsevier
Advances in high-throughput sequencing techniques and bioinformatic analysis have
refuted the “junk” RNA hypothesis that was claimed against non-coding RNAs (ncRNAs) …
refuted the “junk” RNA hypothesis that was claimed against non-coding RNAs (ncRNAs) …
[HTML][HTML] Circular RNAs as potential biomarkers in breast cancer
Due to the high heterogeneity and initially asymptomatic nature of breast cancer (BC), the
management of this disease depends on imaging together with immunohistochemical and …
management of this disease depends on imaging together with immunohistochemical and …
[HTML][HTML] The tumorigenic role of circular RNA-MicroRNA Axis in cancer
WR Kim, EG Park, DH Lee, YJ Lee, WH Bae… - International Journal of …, 2023 - mdpi.com
Circular RNAs (circRNAs) are a class of endogenous RNAs that control gene expression at
the transcriptional and post-transcriptional levels. Recent studies have increasingly …
the transcriptional and post-transcriptional levels. Recent studies have increasingly …
[HTML][HTML] Exosomal circular RNAs: New player in breast cancer progression and therapeutic targets
BM Hussen, S Mohamadtahr, SR Abdullah… - Frontiers in …, 2023 - frontiersin.org
Breast cancer is the most prevalent type of malignancy among women. Exosomes are
extracellular vesicles of cell membrane origin that are released via exocytosis. Their cargo …
extracellular vesicles of cell membrane origin that are released via exocytosis. Their cargo …
[HTML][HTML] Non-Coding RNAs: Foes or Friends for Targeting Tumor Microenvironment
A Szymanowska, C Rodriguez-Aguayo… - Non-coding RNA, 2023 - mdpi.com
Non-coding RNAs (ncRNAs) are a group of molecules critical for cell development and
growth regulation. They are key regulators of important cellular pathways in the tumor …
growth regulation. They are key regulators of important cellular pathways in the tumor …
[HTML][HTML] miRNAs in regulation of tumor microenvironment, chemotherapy resistance, immunotherapy modulation and miRNA therapeutics in cancer
miRNAs are 20–22 long nucleotide non-coding ribonucleic acid molecules critical to the
modulation of molecular pathways. Immune evasion and the establishment of a suitable …
modulation of molecular pathways. Immune evasion and the establishment of a suitable …
[HTML][HTML] Transcriptomics-based liquid biopsy panel for early non-invasive identification of peritoneal recurrence and micrometastasis in locally advanced gastric …
P Ding, H Wu, J Wu, T Li, R Gu, L Zhang… - Journal of Experimental …, 2024 - Springer
Background This study aimed to develop a novel six-gene expression biomarker panel to
enhance the early detection and risk stratification of peritoneal recurrence and …
enhance the early detection and risk stratification of peritoneal recurrence and …
[HTML][HTML] Circular RNAs in EMT-driven metastasis regulation: modulation of cancer cell plasticity, tumorigenesis and therapy resistance
M Ashrafizadeh, J Dai, P Torabian, N Nabavi… - Cellular and Molecular …, 2024 - Springer
The non-coding RNAs comprise a large part of human genome lack of capacity in encoding
functional proteins. Among various members of non-coding RNAs, the circular RNAs …
functional proteins. Among various members of non-coding RNAs, the circular RNAs …
[HTML][HTML] Mimic miRNA and Anti-miRNA Activated Scaffolds as a Therapeutic Strategy to Promote Bone, Cartilage, and Skin Regeneration
G Guelfi, C Capaccia, P Anipchenko, F Ciancabilla… - Macromol, 2024 - mdpi.com
MiRNA-based therapies represent an innovative and promising strategy applicable to
various medical fields, such as tissue regeneration and the treatment of numerous diseases …
various medical fields, such as tissue regeneration and the treatment of numerous diseases …