Circulating tumor DNA in biliary tract cancer: current evidence and future perspectives

A Rizzo, AD Ricci, S Tavolari… - Cancer genomics & …, 2020 - cgp.iiarjournals.org
Peripheral blood of cancer patients “physiologically” presents cells and cellular components
deriving from primary or metastatic sites, including circulating tumor cells (CTCs), circulating …

[HTML][HTML] Do circulating tumor cells, exosomes, and circulating tumor nucleic acids have clinical utility?: a report of the association for molecular pathology

B Gold, M Cankovic, LV Furtado, F Meier… - The Journal of Molecular …, 2015 - Elsevier
Diagnosing and screening for tumors through noninvasive means represent an important
paradigm shift in precision medicine. In contrast to tissue biopsy, detection of circulating …

Circulating tumor cell status monitors the treatment responses in breast cancer patients: a meta-analysis

WT Yan, X Cui, Q Chen, YF Li, YH Cui, Y Wang… - Scientific reports, 2017 - nature.com
Whether circulating tumor cells (CTCs) can be used as an indicator of treatment response in
breast cancer (BC) needs to be clarified. We addressed this issue by a meta-analysis …

Prognostic impact of circulating tumor cells for breast cancer patients treated in the neoadjuvant" Geparquattro" trial

S Riethdorf, V Müller, S Loibl, V Nekljudova… - Clinical Cancer …, 2017 - AACR
Purpose: This study aimed to evaluate the prognostic impact of circulating tumor cells (CTC)
detected in patients with operable or locally advanced breast cancer before and after …

Gene expression signatures in circulating tumor cells correlate with response to therapy in metastatic breast cancer

M Bredemeier, P Edimiris, P Mach, M Kubista… - Clinical …, 2017 - academic.oup.com
BACKGROUND Circulating tumor cells (CTCs) are thought to be an ideal surrogate marker
to monitor disease progression in metastatic breast cancer (MBC). We investigated the …

[HTML][HTML] Isolation, primary culture, morphological and molecular characterization of circulating tumor cells in gynecological cancers

K Kolostova, J Spicka, R Matkowski… - American journal of …, 2015 - ncbi.nlm.nih.gov
The focus of the study was to implement a new workflow for circulating tumor cells (CTCs)
characterization that would allow the analysis of CTCs on a cytomorphological and …

Real-time RT-PCR systems for CTC detection from blood samples of breast cancer and gynaecological tumour patients

U Andergassen, AC Kölbl, S Mahner… - Oncology …, 2016 - spandidos-publications.com
Cells, which detach from a primary epithelial tumour and migrate through lymphatic vessels
and blood stream are called 'circulating tumour cells'. These cells are considered to be the …

An optimised direct lysis method for gene expression studies on low cell numbers

A Viet-Phuong Le, D Huang, T Blick, EW Thompson… - Scientific reports, 2015 - nature.com
There is increasing interest in gene expression analysis of either single cells or limited
numbers of cells. One such application is the analysis of harvested circulating tumour cells …

Next-generation sequencing (NGS) analysis on single circulating tumor cells (CTCs) with no need of whole-genome amplification (WGA)

R Palmirotta, D Lovero, E Silvestris… - Cancer genomics & …, 2017 - cgp.iiarjournals.org
Background: Isolation and genotyping of circulating tumor cells (CTCs) is gaining an
increasing interest by clinical researchers in oncology not only for investigative purposes …

Prognosis of castration-resistant prostate cancer patients–use of the AdnaTest® system for detection of circulating tumor cells

O Čapoun, V Mikulova, M Jančíková… - Anticancer …, 2016 - ar.iiarjournals.org
Background: Detection of circulating tumor cells (CTC) in patients with castration-resistant
prostate cancer (CRPC) may improve the estimate of chemotherapy response. We …