[HTML][HTML] Liver fibrosis in non-alcoholic fatty liver disease: from liver biopsy to non-invasive biomarkers in diagnosis and treatment

LJM Heyens, D Busschots, GH Koek, G Robaeys… - Frontiers in …, 2021 - frontiersin.org
An increasing percentage of people have or are at risk to develop non-alcoholic fatty liver
disease (NAFLD) worldwide. NAFLD comprises different stadia going from isolated steatosis …

Pathophysiology of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis

V Manne, P Handa, KV Kowdley - Clinics in liver disease, 2018 - liver.theclinics.com
The pathophysiology of NAFL and NASH is complex and numerous intermediaries are
involved. Each year brings new and exciting developments as pieces of the …

[HTML][HTML] Clinical and molecular biomarkers for diagnosis and staging of NAFLD

S Di Mauro, A Scamporrino, A Filippello… - International journal of …, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is the most common hepatic pathology in
industrialized countries, affecting about 25% of the general population. NAFLD is a benign …

[HTML][HTML] Nonalcoholic fatty liver disease and type 2 diabetes: where do Diabetologists stand?

S Tomah, N Alkhouri, O Hamdy - Clinical diabetes and endocrinology, 2020 - Springer
Background Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver
disease worldwide. The increasing prevalence of NAFLD mirrors that of obesity and type 2 …

Diagnosis and evaluation of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis, including noninvasive biomarkers and transient elastography

E Tsai, TP Lee - Clinics in liver disease, 2018 - liver.theclinics.com
Nonalcoholic fatty liver disease (NAFLD) is the most common cause of abnormal liver tests
in industrial countries. It encompasses the spectrum of liver damage from simple steatosis to …

[HTML][HTML] New magnetic resonance imaging index for renal fibrosis assessment: a comparison between diffusion-weighted imaging and T1 mapping with histological …

I Friedli, LA Crowe, L Berchtold, S Moll, K Hadaya… - Scientific reports, 2016 - nature.com
A need exists to noninvasively assess renal interstitial fibrosis, a common process to all
kidney diseases and predictive of renal prognosis. In this translational study, Magnetic …

[HTML][HTML] Normal and fibrotic rat livers demonstrate shear strain softening and compression stiffening: a model for soft tissue mechanics

M Perepelyuk, LK Chin, X Cao, A Van Oosten… - PloS one, 2016 - journals.plos.org
Tissues including liver stiffen and acquire more extracellular matrix with fibrosis. The
relationship between matrix content and stiffness, however, is non-linear, and stiffness is …

The triglycerides and glucose (TyG) index: A new marker associated with nonalcoholic steatohepatitis (NASH) in obese patients

B Rivière, A Jaussent, V Macioce, S Faure… - Diabetes & …, 2022 - Elsevier
Aim Diagnosis of nonalcoholic steatohepatitis (NASH) relies on liver biopsy. Noninvasive
tools would be useful to target patients to refer for a biopsy. We aimed to determine the …

[HTML][HTML] The use of two-dimensional shear wave elastography in people with obesity for the assessment of liver fibrosis in non-alcoholic fatty liver disease

R Chimoriya, MK Piya, D Simmons… - Journal of clinical …, 2020 - mdpi.com
Obesity is associated with significant comorbidities, including non-alcoholic fatty liver
disease (NAFLD). Given its potential to progress to advanced liver disease, monitoring the …

Noninvasive diagnosis of nonalcoholic fatty liver disease: are we there yet?

N Alkhouri, AE Feldstein - Metabolism, 2016 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) has rapidly become the most common form of
chronic liver disease in the United States affecting approximately 80–100 million Americans …