The IL-17 family of cytokines in health and disease
The interleukin 17 (IL-17) family of cytokines contains 6 structurally related cytokines, IL-17A
through IL-17F. IL-17A, the prototypical member of this family, just passed the 25 th …
through IL-17F. IL-17A, the prototypical member of this family, just passed the 25 th …
Cold shock proteins: from cellular mechanisms to pathophysiology and disease
JA Lindquist, PR Mertens - Cell Communication and Signaling, 2018 - Springer
Cold shock proteins are multifunctional RNA/DNA binding proteins, characterized by the
presence of one or more cold shock domains. In humans, the best characterized members of …
presence of one or more cold shock domains. In humans, the best characterized members of …
Identification of new key genes for type 1 diabetes through construction and analysis of protein–protein interaction networks based on blood and pancreatic islet …
N Safari‐Alighiarloo, M Taghizadeh… - Journal of …, 2017 - Wiley Online Library
背景1 型糖尿病(T1D) 是一种自身免疫性疾病, 其特征是胰腺β 细胞被浸润的免疫细胞所破坏.
有观点认为在T1D 的进展过程中胰岛β 细胞与免疫细胞具有双向的协同作用 …
有观点认为在T1D 的进展过程中胰岛β 细胞与免疫细胞具有双向的协同作用 …
Differential expression patterns of cytokines in complex regional pain syndrome
Complex regional pain syndromes (CRPS) are characterized by persistent and severe pain
after trauma or surgery. Neuro-immune alterations are assumed to play a pathophysiological …
after trauma or surgery. Neuro-immune alterations are assumed to play a pathophysiological …
Posttranscriptional gene regulation by RNA-binding proteins during oxidative stress: implications for cellular senescence
To respond adequately to oxidative stress, mammalian cells elicit rapid and tightly controlled
changes in gene expression patterns. Besides alterations in the subsets of transcribed …
changes in gene expression patterns. Besides alterations in the subsets of transcribed …
RNA viruses: hijacking the dynamic nucleolus
JA Hiscox - Nature Reviews Microbiology, 2007 - nature.com
The nucleolus is a dynamic subnuclear structure with roles in ribosome subunit biogenesis,
mediation of cell-stress responses and regulation of cell growth. The proteome and structure …
mediation of cell-stress responses and regulation of cell growth. The proteome and structure …
Posttranscriptional orchestration of an anti-apoptotic program by HuR
The RNA-binding protein HuR can stabilize and/or regulate the translation of target mRNAs,
thereby affecting the cellular responses to immune, proliferative, and damaging agents …
thereby affecting the cellular responses to immune, proliferative, and damaging agents …
High mobility group box 1 protein is released by neural cells upon different stresses and worsens ischemic neurodegeneration in vitro and in vivo
High mobility group proteins are chromatin binding factors with key roles in maintenance of
nuclear homeostasis. The evidence indicates that extracellularly released high mobility …
nuclear homeostasis. The evidence indicates that extracellularly released high mobility …
The favorable IFNL3 genotype escapes mRNA decay mediated by AU-rich elements and hepatitis C virus–induced microRNAs
AP McFarland, SM Horner, A Jarret, RC Joslyn… - Nature …, 2014 - nature.com
IFNL3, which encodes interferon-λ3 (IFN-λ3), has received considerable attention in the
hepatitis C virus (HCV) field, as many independent genome-wide association studies have …
hepatitis C virus (HCV) field, as many independent genome-wide association studies have …
The immunobiology of Henoch–Schönlein purpura
YH Yang, YH Chuang, LC Wang, HY Huang… - Autoimmunity …, 2008 - Elsevier
Henoch–Schönlein purpura (HSP) is a common but enigmatic systemic small vessel
vasculitis that primarily affects children. Although the etiology of this disease is unknown …
vasculitis that primarily affects children. Although the etiology of this disease is unknown …