[HTML][HTML] Vanillin-based functionalization strategy to construct multifunctional microspheres for treating inflammation and regenerating intervertebral disc

Z Zhu, Q Yu, H Li, F Han, Q Guo, H Sun, H Zhao, Z Tu… - Bioactive Materials, 2023 - Elsevier
Intervertebral disc degeneration (IVDD) is one of the main causes of low back pain. Although
local delivery strategies using biomaterial carriers have shown potential for IVDD treatment …

Biomaterial engineering for cell transplantation

A Samadi, A Moammeri, S Azimi, BM Bustillo-Perez… - Biomaterials …, 2024 - Elsevier
The current paradigm of medicine is mostly designed to block or prevent pathological
events. Once the disease-led tissue damage occurs, the limited endogenous regeneration …

Injectable and Microporous Microgel Assembly with Sequential Bioactive Factor Release for the Endogenous Repair of Nucleus Pulposus

H Luo, Z Wang, F Yu, Z Zhou, J Wang… - Advanced Functional …, 2024 - Wiley Online Library
Harnessing endogenous stem/progenitor cells to enhance extracellular matrix (ECM)
deposition in the nucleus pulposus (NP) is considered as a potential treatment for …

[HTML][HTML] Transplantation of active nucleus pulposus cells with a keep-charging hydrogel microsphere system to rescue intervertebral disc degeneration

Y Tang, K Zhang, H Zhou, C Zhang, Z Liu… - Journal of …, 2023 - Springer
Background Cell transplantation has been demonstrated as a promising approach in tissue
regeneration. However, the reactive oxygen species (ROS) accumulation and inflammation …

The Emerging Roles of Nanocarrier Drug Delivery System in Treatment of Intervertebral Disc Degeneration-Current Knowledge, Hot Spots, Challenges and Future …

Y Hu, R Yang, S Liu, Z Song… - Drug Design, Development …, 2024 - Taylor & Francis
Low back pain (LBP) is a common condition that has substantial consequences on
individuals and society, both socially and economically. The primary contributor to LBP is …

[PDF][PDF] LOS EXOSOMAS SON UNA NUEVA ESTRATEGIA TERAPÉUTICA PARA LA MEJORÍA DEL DOLOR LUMBAR. REVISIÓN DE LA LITERATURA

JA Sierra-Peña, JC Acevedo-González - resed.es
El dolor lumbar es un problema de salud común que afecta a una gran cantidad de
personas en todo el mundo. Entre las principales causas de este dolor se encuentra el …