The endocannabinoid system as an emerging target of pharmacotherapy
The recent identification of cannabinoid receptors and their endogenous lipid ligands has
triggered an exponential growth of studies exploring the endocannabinoid system and its …
triggered an exponential growth of studies exploring the endocannabinoid system and its …
Cannabinoids as novel anti-inflammatory drugs
P Nagarkatti, R Pandey, SA Rieder… - Future medicinal …, 2009 - Taylor & Francis
Cannabinoids are a group of compounds that mediate their effects through cannabinoid
receptors. The discovery of Δ9-tetrahydrocannabinol (THC) as the major psychoactive …
receptors. The discovery of Δ9-tetrahydrocannabinol (THC) as the major psychoactive …
Cannabinoid CB2 receptor: a new target for controlling neural cell survival?
Two types of cannabinoid receptor have been cloned and characterized. Whereas CB 1
receptors are ubiquitously expressed in neurons of the CNS, CB 2 receptors have been …
receptors are ubiquitously expressed in neurons of the CNS, CB 2 receptors have been …
Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis
SD McAllister, R Murase, RT Christian, D Lau… - Breast cancer research …, 2011 - Springer
Invasion and metastasis of aggressive breast cancer cells are the final and fatal steps during
cancer progression. Clinically, there are still limited therapeutic interventions for aggressive …
cancer progression. Clinically, there are still limited therapeutic interventions for aggressive …
Cannabis, cannabinoids and cannabis-based medicines in cancer care
DI Abrams - Integrative cancer therapies, 2022 - journals.sagepub.com
As medical cannabis becomes legal in more states, cancer patients are increasingly
interested in the potential utility of the ancient botanical in their treatment regimen. Although …
interested in the potential utility of the ancient botanical in their treatment regimen. Although …
Integrating cannabis into clinical cancer care
DI Abrams - Current oncology, 2016 - mdpi.com
Cannabis species have been used as medicine for thousands of years; only since the 1940s
has the plant not been widely available for medical use. However, an increasing number of …
has the plant not been widely available for medical use. However, an increasing number of …
The endocannabinoid system: drug targets, lead compounds, and potential therapeutic applications
DM Lambert, CJ Fowler - Journal of medicinal chemistry, 2005 - ACS Publications
As far as can be ascertained from archeological sources, preparations of the hemp
Cannabis sativa L. were widely used by humans for either therapeutic or ritual purposes in …
Cannabis sativa L. were widely used by humans for either therapeutic or ritual purposes in …
The antitumor activity of plant-derived non-psychoactive cannabinoids
SD McAllister, L Soroceanu, PY Desprez - Journal of neuroimmune …, 2015 - Springer
As a therapeutic agent, most people are familiar with the palliative effects of the primary
psychoactive constituent of Cannabis sativa (CS), Δ 9-tetrahydrocannabinol (THC), a …
psychoactive constituent of Cannabis sativa (CS), Δ 9-tetrahydrocannabinol (THC), a …
Δ9-Tetrahydrocannabinol Inhibits Cell Cycle Progression in Human Breast Cancer Cells through Cdc2 Regulation
MM Caffarel, D Sarrió, J Palacios, M Guzmán… - Cancer research, 2006 - AACR
It has been proposed that cannabinoids are involved in the control of cell fate. Thus, these
compounds can modulate proliferation, differentiation, and survival in different manners …
compounds can modulate proliferation, differentiation, and survival in different manners …
Cannabinoid receptor as a novel target for the treatment of prostate cancer
Cannabinoids, the active components of Cannabis sativa Linnaeus (marijuana) and their
derivatives have received renewed interest in recent years due to their diverse …
derivatives have received renewed interest in recent years due to their diverse …