Mechanical ventilation in acute respiratory distress syndrome: The open lung revisited

L Amado-Rodríguez, C Del Busto, E García-Prieto… - Medicina intensiva, 2017 - Elsevier
Acute respiratory distress syndrome (ARDS) is still related to high mortality and morbidity
rates. Most patients with ARDS will require ventilatory support. This treatment has a direct …

Metabolic imaging and biological assessment: platforms to evaluate acute lung injury and inflammation

M Pourfathi, SJ Kadlecek, S Chatterjee… - Frontiers in …, 2020 - frontiersin.org
Pulmonary inflammation is a hallmark of several pulmonary disorders including acute lung
injury and acute respiratory distress syndrome. Moreover, it has been shown that patients …

Quantitative imaging of alveolar recruitment with hyperpolarized gas MRI during mechanical ventilation

M Cereda, K Emami, S Kadlecek… - Journal of applied …, 2011 - journals.physiology.org
The aim of this study was to assess the utility of 3He MRI to noninvasively probe the effects
of positive end-expiratory pressure (PEEP) maneuvers on alveolar recruitment and …

Positron emission tomography in the COVID-19 pandemic era

C Jin, X Luo, S Qian, K Zhang, Y Gao, R Zhou… - European journal of …, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19) has become a major public health problem
worldwide since its outbreak in 2019. Currently, the spread of COVID-19 is far from over, and …

[HTML][HTML] Advances in PET to assess pulmonary inflammation: a systematic review

L Vass, M Fisk, S Lee, FJ Wilson, J Cheriyan… - European Journal of …, 2020 - Elsevier
Background Respiratory diseases are one of the leading causes of death worldwide, yet
effective treatment options remain limited. Although inflammation is thought to be a key …

Nuclear medicine in times of COVID-19: how radiopharmaceuticals could help to fight the current and future pandemics

F Neumaier, BD Zlatopolskiy, B Neumaier - Pharmaceutics, 2020 - mdpi.com
The emergence and global spread of COVID-19, an infectious disease caused by the novel
coronavirus SARS-CoV-2, has resulted in a continuing pandemic threat to global health …

Evaluating the Berlin Definition in pediatric ARDS

RG Khemani, DF Wilson, A Esteban… - Intensive Care …, 2013 - Springer
Since its original description in 1967 [1], there have been various attempts to use clinical
criteria to define the acute respiratory distress syndrome (ARDS). The 1994 American …

[HTML][HTML] Feasibility of 68Ga-labeled Siglec-9 peptide for the imaging of acute lung inflammation: a pilot study in a porcine model of acute respiratory distress syndrome

J Retamal, J Sörensen, M Lubberink… - American journal of …, 2016 - ncbi.nlm.nih.gov
There is an unmet need for noninvasive, specific and quantitative imaging of inherent
inflammatory activity. Vascular adhesion protein-1 (VAP-1) translocates to the luminal …

Advances in microscopy and complementary imaging techniques to assess the fate of drugs ex vivo in respiratory drug delivery: an invited paper

CW Park, YS Rhee, FG Vogt, D Hayes Jr… - Advanced drug delivery …, 2012 - Elsevier
The technical advances in microscopy imaging techniques have been applied to assess the
fate of drugs for researching respiratory drug delivery in ex vivo and in vivo experiments …

Pre-treatment with allopurinol or uricase attenuates barrier dysfunction but not inflammation during murine ventilator-induced lung injury

MT Kuipers, H Aslami, APJ Vlaar, NP Juffermans… - PloS one, 2012 - journals.plos.org
Introduction Uric acid released from injured tissue is considered a major endogenous
danger signal and local instillation of uric acid crystals induces acute lung inflammation via …