The health effects of vitamin D supplementation: evidence from human studies

R Bouillon, D Manousaki, C Rosen… - Nature Reviews …, 2022 - nature.com
Vitamin D supplementation can prevent and cure nutritional rickets in infants and children.
Preclinical and observational data suggest that the vitamin D endocrine system has a wide …

2019 American College of Rheumatology/Arthritis Foundation guideline for the management of osteoarthritis of the hand, hip, and knee

SL Kolasinski, T Neogi, MC Hochberg… - Arthritis & …, 2020 - Wiley Online Library
Objective To develop an evidence‐based guideline for the comprehensive management of
osteoarthritis (OA) as a collaboration between the American College of Rheumatology …

Vitamin D deficiency increases mortality risk in the UK Biobank: a nonlinear Mendelian randomization study

JP Sutherland, A Zhou, E Hyppönen - Annals of internal medicine, 2022 - acpjournals.org
Background: Low vitamin D status is associated with increased mortality, but randomized
trials on severely deficient participants are lacking. Objective: To assess genetic evidence …

Efficacy of vitamin D3 supplementation on cancer mortality: Systematic review and individual patient data meta-analysis of randomised controlled trials

S Kuznia, A Zhu, T Akutsu, JE Buring… - Ageing research …, 2023 - Elsevier
To evaluate the effect of vitamin D 3 supplementation on cancer mortality in the general
population and on prognosis in cancer patients, a systematic review and meta-analysis of …

[HTML][HTML] Vitamin D and multiple health outcomes: an umbrella review of observational studies, randomized controlled trials, and Mendelian randomization studies

D Liu, X Meng, Q Tian, W Cao, X Fan, L Wu, M Song… - Advances in …, 2022 - Elsevier
Observational studies, randomized controlled trials (RCTs), and Mendelian randomization
(MR) studies have yielded inconsistent results on the associations of vitamin D …

Vitamin D supplementation and total cancer incidence and mortality by daily vs. infrequent large-bolus dosing strategies: a meta-analysis of randomised controlled …

N Keum, QY Chen, DH Lee, JE Manson… - British journal of …, 2022 - nature.com
Background Efficacy of vitamin D supplementation may vary by dosing strategies and
adiposity. To address such heterogeneity, we performed a meta-analysis of randomised …

L-shaped association of serum 25-hydroxyvitamin D concentrations with cardiovascular and all-cause mortality in individuals with osteoarthritis: results from the …

Q Xiao, B Cai, A Yin, H Huo, K Lan, G Zhou, L Shen… - BMC medicine, 2022 - Springer
Background The relationship between vitamin D status and mortality in patients with
osteoarthritis (OA) is unknown. This study investigated the associations of serum 25 …

Serum 25-hydroxyvitamin D and cancer risk: a systematic review of Mendelian randomization studies

T Lawler, S Warren Andersen - Nutrients, 2023 - mdpi.com
Epidemiological studies suggest that higher serum 25-hydroxyvitamin D is associated with
lower risk for several cancers, including breast, prostate, colorectal, and lung cancers. To …

25-Hydroxyvitamin D status, vitamin D intake, and skin cancer risk: a systematic review and dose–response meta-analysis of prospective studies

Y Mahamat-Saleh, D Aune, S Schlesinger - Scientific Reports, 2020 - nature.com
Sun exposure is a major environmental risk factor for skin cancers and is also an important
source of vitamin D. However, while experimental evidence suggests that vitamin D may …

Systematic review of Mendelian randomization studies on risk of cancer

G Markozannes, A Kanellopoulou, O Dimopoulou… - BMC medicine, 2022 - Springer
Background We aimed to map and describe the current state of Mendelian randomization
(MR) literature on cancer risk and to identify associations supported by robust evidence …