Bipolar disorder (BP) is a chronic neuropsychiatric condition characterized by pathological
fluctuations in mood from mania to depression. Adoption, twin and family studies have …

Dopamine-glutamate interplay dysfunctions have been suggested as pathophysiological
key determinants of major psychotic disorders, above all schizophrenia and mood disorders …

While most of the efforts to uncover mechanisms contributing to bipolar disorder (BD)
focused on phenotypes at the mature neuron stage, little research has considered events …

Major depressive disorder (MDD), bipolar disorder (BD), and schizophrenia (SCZ) are
classified as major mental disorders and together account for the second-highest global …

The first mutation in a gene associated with a neuronal migration disorder was identified in
patients with Kallmann Syndrome, characterized by hypogonadotropic hypogonadism and …

Background Cannabis use is a risk factor of psychiatric illness, such as bipolar disorder type-
I (BDI). Indeed, cannabis use strongly influences the onset and clinical course of BDI …

Primary cilium (PC) is a microtubule-rich organelle that protrudes from the plasma
membrane and acts as a cellular antenna sensing extracellular signals during brain …

The lifetime presence of psychotic symptoms is associated with more clinical severity, poorer
outcome and biological changes in patients affected by bipolar disorder (BD). Epigenetic …

Radial migration of pyramidal neurons is an important event during the development of
cerebral cortex. Neurons experience series of morphological and directional transitions to …

Schizophrenia is a highly heritable psychiatric disorder linked to a large number of risk
genes. The function of these genes in disease etiology is not fully understood but pathway …