Diseases of the central nervous system (CNS) are challenging to treat, mainly due to the
blood-brain barrier (BBB), which restricts drugs in circulation from entering target regions in …

Data on the effectiveness of transcranioplasty ultrasonography (TCUS) through sonolucent
cranioplasty (SC) is new and heterogeneous. We performed the first systematic literature …

Focused ultrasound (FUS) has emerged as a promising area of research in neuro-oncology.
Preclinical and clinical investigation has demonstrated the utility of FUS in therapeutic …

With the recent advances in medicine, human life expectancy is increasing; however, the
extra years of life are not necessarily spent in good health or free from disability, resulting in …

Introduction: Histotripsy is a non-thermal focused ultrasound therapy in development for the
non-invasive ablation of cancerous tumors. Intracranial histotripsy has been limited by …

Over the years, there has been a significant transformation in the field of neuroimaging
modalities, spanning Dandy's use of x-rays for ventriculography and …

Neurosurgical procedures heavily rely on technological innovation to improve patients care.
Focused Ultrasound (FUS) represents a novel and ever-growing technology with roots …

To the Editor: We were captivated by the recent cover article by Lee et al 1 titled “First
Experience With Postoperative Transcranial Ultrasound Through Sonolucent Burr Hole …

There are very few models able to simulate with precision the complex structure of the blood-
brain barrier (BBB): our body's most restrictive barrier which, while protecting our brain from …

US-induced BBB opening was performed on an isolated guinea pig brain maintained in vitro
by arterial perfusion, a unique experimental preparation in which the BBB is morphologically …