Strategies, models and biomarkers in experimental non-alcoholic fatty liver disease research

J Willebrords, IVA Pereira, M Maes, SC Yanguas… - Progress in lipid …, 2015 - Elsevier
Non-alcoholic fatty liver disease encompasses a spectrum of liver diseases, including
simple steatosis, steatohepatitis, liver fibrosis and cirrhosis and hepatocellular carcinoma …

[HTML][HTML] Cutaneous adverse reactions of amiodarone

K Jaworski, I Walecka, L Rudnicka… - … medical journal of …, 2014 - ncbi.nlm.nih.gov
Dermatological complications of amiodarone are commonly encountered problems in
therapy. The incidence in the population of patients with prolonged use of amiodarone …

Amiodarone-associated optic neuropathy: a critical review

RS Passman, CL Bennett, JM Purpura, R Kapur… - The American journal of …, 2012 - Elsevier
Although amiodarone is the most commonly prescribed anti-arrhythmic drug, its use is
limited by serious toxicities, including optic neuropathy. Current reports of amiodarone …

Deconjugated‐Ketone‐Derived Dienolates in Remote, Stereocontrolled, Aromative aza‐Diels‐Alder Cycloaddition

S Frankowski, A Skrzyńska, L Sieroń… - Advanced Synthesis & …, 2020 - Wiley Online Library
In the manuscript, the application of β, γ‐unsaturated ketones as precursors of electron‐rich
dienophiles in the organocatalytic, aromative inverse‐electron‐demand hetero‐Diels‐Alder …

[HTML][HTML] KCNQ5 potassium channel activation underlies vasodilation by tea

KE Redford, S Rognant, TA Jepps… - Cellular physiology and …, 2021 - ncbi.nlm.nih.gov
Methods: We applied electrophysiology, myography, mass spectrometry and in silico
docking to determine effects and their underlying molecular mechanisms of tea and its …

[PDF][PDF] Cardio-thyrotoxicosis syndrome: a review of thyrotoxic cardiovascular disease

PB Bhattad, M Roumia - Cureus, 2023 - cureus.com
Thyrotoxicosis, an endocrine disorder characterized by elevated serum thyroid hormone
levels of triiodothyronine (T3) and/or thyroxine (T4), can impact cardiovascular health in …

Metabolite identification studies on amiodarone in in vitro (rat liver microsomes, rat and human liver S9 fractions) and in vivo (rat feces, urine, plasma) matrices by …

NR Varkhede, S Jhajra, DS Ahire… - … in Mass Spectrometry, 2014 - Wiley Online Library
RATIONALE Several mechanisms have been anticipated for the toxicity of amiodarone, such
as oxidative stress, lipid peroxidation, phospholipidosis, free radical generation, etc …

Synthesis of a novel class of benzofurans via a three-component, regiospecific intramolecular heterocylization reaction

B Karami, S Khodabakhshi, F Hashemi - Tetrahedron Letters, 2013 - Elsevier
A new, convenient, and environmentally benign three-component synthesis of a novel class
of benzofurans is developed by condensing different arylglyoxals, benzamide, and phenolic …

Amiodarone sensitizes human glioma cells but not astrocytes to TRAIL-induced apoptosis via CHOP-mediated DR5 upregulation

IY Kim, YJ Kang, MJ Yoon, EH Kim, SU Kim… - Neuro …, 2011 - academic.oup.com
Amiodarone is a widely used anti-arrhythmic drug that inhibits diverse ion channels,
including the Na+/Ca2+ exchanger (NCX), L-type Ca2+ channels, and Na+ channels. Here …

Controlled Synthesis of 2- and 3-Substituted Benzo[b]furans

T Pei, C Chen, L DiMichele, IW Davies - Organic Letters, 2010 - ACS Publications
A controlled regioselective synthesis of either C-2 or C-3 substituted benzo [b] furans from
readily accessible 1-(2-hydroxyphenyl)-2-chloroethanones is described. Addition of a range …