[HTML][HTML] SARS-CoV-2 variant biology: immune escape, transmission and fitness

AM Carabelli, TP Peacock, LG Thorne… - Nature Reviews …, 2023 - nature.com
In late 2020, after circulating for almost a year in the human population, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibited a major step change in its …

[HTML][HTML] The role of SARS-CoV-2 accessory proteins in immune evasion

M Zandi, M Shafaati, D Kalantar-Neyestanaki… - Biomedicine & …, 2022 - Elsevier
Many questions on the SARS-CoV-2 pathogenesis remain to answer. The SARS-CoV-2
genome encodes some accessory proteins that are essential for infection. Notably …

SARS-CoV-2 infection and persistence in the human body and brain at autopsy

SR Stein, SC Ramelli, A Grazioli, JY Chung, M Singh… - Nature, 2022 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) is known to cause multi-organ dysfunction,–
during acute infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

SARS‐CoV‐2 Omicron variant: Immune escape and vaccine development

D Ao, T Lan, X He, J Liu, L Chen, DT Baptista‐Hon… - MedComm, 2022 - Wiley Online Library
New genetic variants of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)
constantly emerge through unmitigated spread of the virus in the ongoing Coronavirus …

Immune mechanisms underlying COVID-19 pathology and post-acute sequelae of SARS-CoV-2 infection (PASC)

S Mohandas, P Jagannathan, TJ Henrich, ZA Sherif… - Elife, 2023 - elifesciences.org
With a global tally of more than 500 million cases of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infections to date, there are growing concerns about the post …

Unique mutations in SARS-CoV-2 Omicron subvariants' non-spike proteins: Potential impacts on viral pathogenesis and host immune evasion

A Hossain, S Akter, AA Rashid, S Khair… - Microbial …, 2022 - Elsevier
SARS-CoV-2 is the causative agent behind the ongoing COVID-19 pandemic. This virus is a
cumulative outcome of mutations, leading to frequent emergence of new variants and their …

The regulation of lncRNAs and miRNAs in SARS-CoV-2 infection

Y Lin, Q Sun, B Zhang, W Zhao, C Shen - Frontiers in Cell and …, 2023 - frontiersin.org
The coronavirus disease 2019 (COVID-19) was a global endemic that continues to cause a
large number of severe illnesses and fatalities. There is increasing evidence that non-coding …

The Delta and Omicron variants of SARS-CoV-2: what we know so far

VP Chavda, R Bezbaruah, K Deka, L Nongrang… - Vaccines, 2022 - mdpi.com
The world has not yet completely overcome the fear of the havoc brought by SARS-CoV-2.
The virus has undergone several mutations since its initial appearance in China in …

[HTML][HTML] MEF2A suppresses stress responses that trigger DDX41-dependent IFN production

JR Smith, JW Dowling, MI McFadden, A Karp… - Cell reports, 2023 - cell.com
Cellular stress in the form of disrupted transcription, loss of organelle integrity, or damage to
nucleic acids can elicit inflammatory responses by activating signaling cascades canonically …

Efficacy of interferon alpha for the treatment of hospitalized patients with COVID-19: A meta-analysis

M Buchynskyi, I Kamyshna, K Lyubomirskaya… - Frontiers in …, 2023 - frontiersin.org
Introduction IFN-α intervention may block SARS-CoV-2 replication and normalize the
deregulated innate immunity of COVID-19. Aim This meta-analysis aimed to investigate the …