[HTML][HTML] Lipoproteins, macrophage function, and atherosclerosis: beyond the foam cell?

DJ Rader, E Puré - Cell metabolism, 2005 - cell.com
Atherogenesis requires and is highly influenced by the interaction between lipoproteins and
macrophages. Most of the focus to date has been on the ability of atherogenic lipoproteins …

Lipoprotein lipase S447X: a naturally occurring gain-of-function mutation

J Rip, MC Nierman, CJ Ross, JW Jukema… - … , and vascular biology, 2006 - Am Heart Assoc
Lipoprotein lipase (LPL) hydrolyzes triglycerides in the circulation and promotes the hepatic
uptake of remnant lipoproteins. Since the gene was cloned in 1989, more than 100 LPL …

Lipolysis of triglyceride-rich lipoproteins, vascular inflammation, and atherosclerosis

EA Schwartz, PD Reaven - Biochimica et Biophysica Acta (BBA)-Molecular …, 2012 - Elsevier
Epidemiological and interventional studies have implicated elevated triglyceride-rich
lipoprotein (TGRL) levels as a risk factor for cardiovascular disease and vascular …

Leptin increases lipoprotein lipase secretion by macrophages: involvement of oxidative stress and protein kinase C

F Maingrette, G Renier - Diabetes, 2003 - Am Diabetes Assoc
Recent data suggest that plasma leptin may represent a cardiovascular risk factor in diabetic
patients. To gain further insight into the role of leptin in atherogenesis associated with …

Polymorphism of the lipoprotein lipase gene and risk of atherothrombotic cerebral infarction in the Japanese

Y Shimo-Nakanishi, T Urabe, N Hattori, Y Watanabe… - Stroke, 2001 - Am Heart Assoc
Background and Purpose—Lipid and lipoprotein abnormalities have been implicated in the
pathogenesis of ischemic cerebrovascular disease and atherosclerosis. Lipoprotein lipase …

The pivotal role of lipoprotein lipase in atherosclerosis

JR Mead, DP Ramji - Cardiovascular research, 2002 - academic.oup.com
1. Introduction acids and 2-monoacylglycerols for tissue utilization [3, 4]. Due to the large
size of its substrates, the physiological site Atherosclerosis, the underlying cause of heart …

Apolipoprotein B-48: a unique marker of chylomicron metabolism

K Nakajima, T Nagamine, MQ Fujita, M Ai… - Advances in clinical …, 2014 - Elsevier
Abstract Apolipoprotein B-48 (apoB-48) is known to be the only specific marker of intestinal
chylomicron particles. The amino acid sequence of apoB-48 represents 48% of the initial …

[HTML][HTML] Role of leptin in atherogenesis

L Dubey, Z Hesong - Experimental & Clinical Cardiology, 2006 - ncbi.nlm.nih.gov
The pathogenesis of atherosclerosis involves multiple cellular events, including endothelial
cell dysfunction, inflammation, proliferation of vascular smooth muscle cells and matrix …

Spontaneous atherosclerosis in aged lipoprotein lipase–deficient mice with severe hypertriglyceridemia on a normal chow diet

X Zhang, R Qi, X Xian, F Yang, M Blackstein… - Circulation …, 2008 - Am Heart Assoc
Large-scale epidemiological studies have revealed a strong association between
hypertriglyceridemia and coronary arteriosclerotic disease. However, there are conflicting …

Anti–lipoprotein lipase antibodies: A new player in the complex atherosclerotic process in systemic lupus erythematosus?

JF de Carvalho, EF Borba, VST Viana… - Arthritis & …, 2004 - Wiley Online Library
Objective The novel description of antibodies to lipoprotein lipase (anti‐LPL) associated with
dyslipoproteinemia prompted us to analyze the association of anti‐LPL with clinical and …