Lipoprotein lipase in the arterial wall: linking LDL to the arterial extracellular matrix and much more

MO Pentikäinen, R Oksjoki, K Öörni… - … , and vascular biology, 2002 - Am Heart Assoc
For low density lipoprotein (LDL) particles to be atherogenic, increasing evidence indicates
that their residence time in the arterial intima must be sufficient to allow their modification …

Lipoprotein lipase and atherosclerosis

Y Stein, O Stein - Atherosclerosis, 2003 - Elsevier
Lipoprotein lipase (LPL) is a key enzyme in catabolism of plasma lipoprotein triglycerides
(TGs), and in that capacity has a salutary influence on plasma HDL, and thus appears to be …

Lipoprotein lipase and atherosclerosis

K Tsutsumi - Current vascular pharmacology, 2003 - ingentaconnect.com
Lipoprotein lipase (LPL) is a rate-limiting enzyme that hydrolyzes circulating triglyceride-rich
lipoprotein such as very low density lipoproteins and chylomicrons. A decrease in LPL …

Long-term treatment of lipoprotein lipase deficiency with medium-chain triglyceride-enriched diet: a case series

L Aljouda, L Nagy, A Schulze - Nutrients, 2023 - mdpi.com
Background: Lipoprotein lipase (LPL) deficiency is a genetic condition. Affected individuals
typically develop symptoms related to severe and persistent hypertriglyceridemia, such as …

Role of extracellular retention of low density lipoproteins in atherosclerosis

J Borén, M Gustafsson, K Skålén, C Flood… - Current opinion in …, 2000 - journals.lww.com
The pathogenesis for atherosclerosis is still unclear, and several hypotheses have been
articulated to explain the initiating events in atherogenesis. Although these hypotheses are …

Short-term triglyceride lowering with fenofibrate improves vasodilator function in subjects with hypertriglyceridemia

WH Capell, CA DeSouza, P Poirier… - … , and vascular biology, 2003 - Am Heart Assoc
Objective—The objective of this study was to investigate the effects of lowering plasma
triglycerides (TGs) on endothelial function and gain insight into the role played by free fatty …

The emergence of sedentary behaviour physiology and its effects on the cardiometabolic profile in young and older adults

DJ Ryan, GK Stebbings, GL Onambele - Age, 2015 - Springer
It has recently emerged that sedentary behaviour is independent of a lack of physical activity
as individuals can be sufficiently active, based on the recommended physical activity …

MicroRNA-467b targets LPL gene in RAW 264.7 macrophages and attenuates lipid accumulation and proinflammatory cytokine secretion

GP Tian, WJ Chen, PP He, SL Tang, GJ Zhao, YC Lv… - Biochimie, 2012 - Elsevier
LPL (lipoprotein lipase) is a rate-limiting enzyme involved in the hydrolysis of triglycerides.
Previous studies have shown that microRNA (miR)-467b regulates hepatic LPL expression …

Local non-esterified fatty acids correlate with inflammation in atheroma plaques of patients with type 2 diabetes

S Mas, R Martínez-Pinna, JL Martín-Ventura… - Diabetes, 2010 - Am Diabetes Assoc
OBJECTIVE Atherosclerosis is prevalent in diabetic patients, but there is little information on
the localization of nonesterified fatty acids (NEFAs) within the plaque and their relationship …

Vascular lipases, inflammation and atherosclerosis

SN Hasham, S Pillarisetti - Clinica Chimica Acta, 2006 - Elsevier
Members of the lipase family that include lipoprotein lipase, hepatic lipase and endothelial
cell lipase play a central role in triglyceride and phospholipid hydrolysis. Because the site of …