[HTML][HTML] A novel role of Sp1 and Sp3 in the interferon-γ-mediated suppression of macrophage lipoprotein lipase gene transcription

TR Hughes, TS Tengku-Muhammad, SA Irvine… - Journal of Biological …, 2002 - ASBMB
The regulation of macrophage lipoprotein lipase by cytokines is of potentially crucial
importance in the pathogenesis of atherosclerosis. We have shown previously that …

[PDF][PDF] Direct effects of long-chain non-esterified fatty acids on vascular cells and their relevance to macrovascular complications of diabetes

JF Oram, KE Bornfeldt - Front Biosci, 2004 - article.imrpress.com
[Frontiers in Bioscience 9, 1240-1253, May 1, 2004] 1240 DIRECT EFFECTS OF LONG-CHAIN
NON-ESTERIFIED FATTY ACIDS ON VASCULAR CEL Page 1 [Frontiers in Bioscience 9 …

Novel combined GPIHBP1 mutations in a patient with hypertriglyceridemia associated with CAD

H Yamamoto, M Onishi, N Miyamoto, R Oki… - … of atherosclerosis and …, 2013 - jstage.jst.go.jp
Aim: Lipoprotein lipase (LPL) deficiency is a rare autosomal recessive disorder
characterized by severe hypertriglyceridemia. Similar clinical phenotypes have been …

Triglyceride-rich lipoproteins and cardiovascular diseases

D Xu, L Xie, C Cheng, F Xue, C Sun - Frontiers in Endocrinology, 2024 - frontiersin.org
The global prevalence of cardiovascular diseases (CVD) continues to rise steadily, making it
a leading cause of mortality worldwide. Atherosclerosis (AS) serves as a primary driver of …

Associations of apolipoprotein E exon 4 and lipoprotein lipase S447X polymorphisms with acute ischemic stroke and myocardial infarction

L Baum, H Keung Ng, KS Wong… - Clinical Chemistry and …, 2006 - degruyter.com
Abstract Background: Because apolipoprotein E (apoE) and lipopoprotein lipase (LPL)
polymorphisms interact with each other and with other factors to affect lipid metabolism, we …

[HTML][HTML] Traditional Chinese medicine for lipid metabolism disorders

Y Li, X Wang, Z Shen - American Journal of Translational Research, 2017 - ncbi.nlm.nih.gov
Dyslipidemia significantly contributes to the development of cardiovascular disease (CVD),
which is the most common cause of morbidity and mortality in China. Statins are the first-line …

Inflammation associated with the postprandial lipolysis of triglyceriderich lipoproteins by lipoprotein lipase

LJ Higgins, JC Rutledge - Current atherosclerosis reports, 2009 - Springer
Although hypertriglyceridemia has repeatedly been implicated as an atherogenic condition,
there are conflicting reports concerning the atherogenicity of products released from …

Expression of LPL in endothelial-intact artery results in lipid deposition and vascular cell adhesion molecule-1 upregulation in both LPL and ApoE-deficient mice

J Wang, X Xian, W Huang, L Chen, L Wu… - … , and vascular biology, 2007 - Am Heart Assoc
Objective—Overexpression of lipoprotein lipase (LPL) in deendothelialized artery led to
profound localized lipid deposition. In this study the role of LPL in atherogenesis in …

Associations between LPL gene polymorphisms and coronary artery disease: evidence based on an updated and cumulative meta-analysis

WQ Ma, Y Wang, XQ Han, Y Zhu, NF Liu - Bioscience reports, 2018 - portlandpress.com
Lipoprotein lipase (LPL) is widely linked to lipid and lipoprotein metabolism, but its effects on
coronary artery disease (CAD) are not clearly elucidated. The aim of the present study was …

Association of lipoprotein base Ser447Ter polymorphism with brain infarction: a population-based neuropathological study

L Myllykangas, T Polvikoski, R Sulkava… - Annals of …, 2001 - Taylor & Francis
BACKGROUND. Variants of the lipoprotein lipase (LPL) gene have been shown to influence
serum lipid levels, risk of coronary heart disease and, as found recently, risk of clinical …