Fluorescence lifetime imaging microscopy: fundamentals and advances in instrumentation, analysis, and applications

R Datta, TM Heaster, JT Sharick… - … of biomedical optics, 2020 - spiedigitallibrary.org
Significance: Fluorescence lifetime imaging microscopy (FLIM) is a powerful technique to
distinguish the unique molecular environment of fluorophores. FLIM measures the time a …

Near-infrared (NIR) lanthanide molecular probes for bioimaging and biosensing

Y Ning, M Zhu, JL Zhang - Coordination Chemistry Reviews, 2019 - Elsevier
Recent advances in NIR detector bloom the design of NIR fluorophores for bioimaging
guided diagnosis and therapeutics, with reduced light-tissue interaction, enhanced signal-to …

Molecularly Engineered Room-Temperature Phosphorescence for Biomedical Application: From the Visible toward Second Near-Infrared Window

B Chang, J Chen, J Bao, T Sun, Z Cheng - Chemical Reviews, 2023 - ACS Publications
Phosphorescence, characterized by luminescent lifetimes significantly longer than that of
biological autofluorescence under ambient environment, is of great value for biomedical …

Towards more accurate bioimaging of drug nanocarriers: turning aggregation-caused quenching into a useful tool

J Qi, X Hu, X Dong, Y Lu, H Lu, W Zhao… - Advanced Drug Delivery …, 2019 - Elsevier
One of the current challenges in the monitoring of drug nanocarriers lies in the difficulties in
discriminating the carrier-bound signals from the bulk signals of probes. Environment …

Towards clinically translatable in vivo nanodiagnostics

S Park, A Aalipour, O Vermesh, JH Yu… - Nature Reviews …, 2017 - nature.com
Nanodiagnostics as a field makes use of fundamental advances in nanobiotechnology to
diagnose, characterize and manage disease at the molecular scale. As these strategies …

[HTML][HTML] Smart probes for optical imaging of T cells and screening of anti-cancer immunotherapies

M Bertolini, MS Wong, L Mendive-Tapia… - Chemical Society …, 2023 - pubs.rsc.org
T cells are an essential part of the immune system with crucial roles in adaptive response
and the maintenance of tissue homeostasis. Depending on their microenvironment, T cells …

A review on Schiff base fluorescent chemosensors for cell imaging applications

D Udhayakumari, V Inbaraj - Journal of fluorescence, 2020 - Springer
Fluorescent determinations of analytes have proven to be a powerful method due to their
simplicity, low cost, detection limit, rapid photoluminescence response, and applicability to …

Bioimaging with upconversion nanoparticles

EM Mettenbrink, W Yang… - Advanced photonics …, 2022 - Wiley Online Library
Bioimaging enables the spatiotemporal visualization of biological processes at various
scales empowered by a range of different imaging modalities and contrast agents …

Sensing and imaging of mitochondrial viscosity in living cells using a red fluorescent probe with a long lifetime

B Chen, C Li, J Zhang, J Kan, T Jiang, J Zhou… - Chemical …, 2019 - pubs.rsc.org
A red fluorescent probe (Mito-V) with a long lifetime was designed to monitor viscosity
changes with high selectivity and sensitivity. The fluorescence intensity and lifetime of Mito-V …

Recent progress in time‐resolved biosensing and bioimaging based on lanthanide‐doped nanoparticles

Q Ma, J Wang, Z Li, X Lv, L Liang, Q Yuan - Small, 2019 - Wiley Online Library
Luminescent nanomaterials have attracted great attention in luminescence‐based
bioanalysis due to their abundant optical and tunable surface physicochemical properties …