Current insights and emerging trends in early-onset type 2 diabetes
Type 2 diabetes diagnosed in childhood or early adulthood is termed early-onset type 2
diabetes. Cases of early-onset type 2 diabetes are increasing rapidly globally, alongside …
diabetes. Cases of early-onset type 2 diabetes are increasing rapidly globally, alongside …
The role of autophagy in the treatment of type II diabetes and its complications: a review
X Zhao, LY Bie, DR Pang, X Li, LF Yang… - Frontiers in …, 2023 - frontiersin.org
Type II diabetes mellitus (T2DM) is a chronic metabolic disease characterized by prolonged
hyperglycemia and insulin resistance (IR). Its incidence is increasing annually, posing a …
hyperglycemia and insulin resistance (IR). Its incidence is increasing annually, posing a …
Antihypertensive and lipid-lowering medication adherence in young adults with youth-onset type 2 diabetes
RS Weinstock, PM Trief, BK Burke, H Wen… - JAMA network …, 2023 - jamanetwork.com
Importance Youth-onset type 2 diabetes is associated with early development of chronic
complications. Treatment of elevated blood pressure (BP), nephropathy, and dyslipidemia …
complications. Treatment of elevated blood pressure (BP), nephropathy, and dyslipidemia …
[HTML][HTML] Prediabetes in children and adolescents: An updated review
HY Ng, LTW Chan - World Journal of Clinical Pediatrics, 2023 - ncbi.nlm.nih.gov
Prediabetes, the precursor of type 2 diabetes mellitus, is an intermediate stage between
normal glucose homeostasis and overt diabetes. This asymptomatic metabolic state is …
normal glucose homeostasis and overt diabetes. This asymptomatic metabolic state is …
[HTML][HTML] Treatment for type 2 diabetes and diabetic nephropathy by targeting Smad3 signaling
H He, H Wang, X Chen, Y Zhong… - … Journal of Biological …, 2024 - ncbi.nlm.nih.gov
TGF-β/Smad3 signaling plays a critical role in type 2 diabetes (T2D) and type 2 diabetic
nephropathy (T2DN), but treatment by specifically targeting Smad3 remains unexplored. To …
nephropathy (T2DN), but treatment by specifically targeting Smad3 remains unexplored. To …
Impaired skeletal muscle regeneration in diabetes: From cellular and molecular mechanisms to novel treatments
E Espino-Gonzalez, E Dalbram, R Mounier, J Gondin… - Cell Metabolism, 2024 - cell.com
Diabetes represents a major public health concern with a considerable impact on human life
and healthcare expenditures. It is now well established that diabetes is characterized by a …
and healthcare expenditures. It is now well established that diabetes is characterized by a …
Sirtuins in kidney diseases: potential mechanism and therapeutic targets
Q Jin, F Ma, T Liu, L Yang, H Mao, Y Wang… - Cell Communication and …, 2024 - Springer
Sirtuins, which are NAD+-dependent class III histone deacetylases, are involved in various
biological processes, including DNA damage repair, immune inflammation, oxidative stress …
biological processes, including DNA damage repair, immune inflammation, oxidative stress …
Insulin Secretion, Sensitivity, and Kidney Function in Young Individuals With Type 2 Diabetes
P Bjornstad, YJ Choi, C Platnick, S Gross… - Diabetes …, 2024 - Am Diabetes Assoc
OBJECTIVE β-Cell dysfunction and insulin resistance magnify the risk of kidney injury in
type 2 diabetes. The relationship between these factors and intraglomerular hemodynamics …
type 2 diabetes. The relationship between these factors and intraglomerular hemodynamics …
Beta cell dysfunction in youth-and adult-onset type 2 diabetes: an extensive narrative review with a special focus on the role of nutrients
A Serbis, V Giapros, K Tsamis, F Balomenou… - Nutrients, 2023 - mdpi.com
Traditionally a disease of adults, type 2 diabetes (T2D) has been increasingly diagnosed in
youth, particularly among adolescents and young adults of minority ethnic groups …
youth, particularly among adolescents and young adults of minority ethnic groups …
Diabetic foot complications among Indigenous peoples in Canada: a scoping review through the PROGRESS-PLUS equity lens
V Blanchette, J Patry, M Brousseau-Foley… - Frontiers in …, 2023 - frontiersin.org
Introduction Indigenous peoples in Canada face a disproportionate burden of diabetes-
related foot complications (DRFC), such as foot ulcers, lower extremity amputations (LEA) …
related foot complications (DRFC), such as foot ulcers, lower extremity amputations (LEA) …