Alzheimer's Disease (AD) is the leading cause of dementia, observed at a higher incidence
in women compared with men. Treatments aimed at improving pathology in AD remain …

The nasal region is one of the distinct environments for the survival of various microbiota.
The human microbial niche begins to inhabit the human body right from birth, and the …

Clarifying the relationships between neuropsychiatric symptoms and Alzheimer's disease
(AD)-related pathology may open avenues for effective treatments. Here, we investigate the …

Background: Gut microbiota can influence human brain function and behavior. Recent
studies showed that gut microbiota might play an important role in the pathogenesis of …

Objectives: To observe the natural time course of noncognitive symptoms before the onset of
symptomatic Alzheimer disease dementia. Methods: Using the National Alzheimer's …

Background Music therapy (MT) aims at maintaining, restoring and furthering
physical/emotional/mental health. This review assesses effectiveness of MT and its methods …

The brainstem locus coeruleus (LC) supplies norepinephrine to the forebrain and
degenerates in Alzheimer's disease (AD). Loss of LC neurons is correlated with increased …

Adenosine exerts an important role in the modulation of central nervous system (CNS)
activity. Through the interaction with four G-protein coupled receptor (GPCR) subtypes …

Environmental enrichment (EE) is an environmental paradigm encompassing sensory,
cognitive, and physical stimulation at a heightened level. Previous studies have reported the …

Alzheimer's disease (AD) remains a major cause of morbidity and mortality worldwide, and
despite extensive research, only a few drugs are available for management of the disease …