[HTML][HTML] Extracellular vesicle-loaded hydrogels for tissue repair and regeneration

Y Ju, Y Hu, P Yang, X Xie, B Fang - Materials Today Bio, 2023 - Elsevier
Extracellular vesicles (EVs) are a collective term for nanoscale or microscale vesicles
secreted by cells that play important biological roles. Mesenchymal stem cells are a class of …

[HTML][HTML] Stem cell-derived exosomes: emerging therapeutic opportunities for wound healing

C Zhou, B Zhang, Y Yang, Q Jiang, T Li, J Gong… - Stem cell research & …, 2023 - Springer
Wound healing is a dynamic and highly sequential process involving a series of overlapping
spatial and temporal phases, including hemostasis, inflammation, proliferation, and tissue …

Current progress, strategy, and prospects of PD-1/PDL-1 immune checkpoint biosensing platforms for cancer diagnostics, therapy monitoring, and drug screening

K Ratajczak, H Grel, P Olejnik, S Jakiela… - Biosensors and …, 2023 - Elsevier
Recent technological advancements in testing and monitoring instrumentation have greatly
contributed to the progress in cancer treatment by surgical, chemotherapeutic and …

MitoEVs: a new player in multiple disease pathology and treatment

X Zhou, S Liu, Y Lu, M Wan, J Cheng… - Journal of Extracellular …, 2023 - Wiley Online Library
Mitochondrial damage plays vital roles in the pathology of many diseases, such as cancers,
neurodegenerative diseases, aging, metabolic diseases and many types of organ injury …

[HTML][HTML] Human umbilical cord mesenchymal stem cells derived exosome shuttling mir-129-5p attenuates inflammatory bowel disease by inhibiting ferroptosis

Z Wei, S Hang, DK Wiredu Ocansey, Z Zhang… - Journal of …, 2023 - Springer
Background Ferroptosis, a unique form of non-apoptotic cell death, is dependent on iron and
lipoperoxidation, and has been shown to be associated with the pathogenesis of …

The landscape of biomimetic nanovesicles in brain diseases

Q You, F Liang, G Wu, F Cao, J Liu, Z He… - Advanced …, 2024 - Wiley Online Library
Brain diseases, such as brain tumors, neurodegenerative diseases, cerebrovascular
diseases, and brain injuries, are caused by various pathophysiological changes, which pose …

MiR‐141‐3p‐Functionalized Exosomes Loaded in Dissolvable Microneedle Arrays for Hypertrophic Scar Treatment

S Meng, Q Wei, S Chen, X Liu, S Cui, Q Huang, Z Chu… - Small, 2024 - Wiley Online Library
Hypertrophic scar (HS) is a common fibroproliferative disease caused by abnormal wound
healing after deep skin injury. However, the existing approaches have unsatisfactory …

[HTML][HTML] Porous microneedle patch with sustained delivery of extracellular vesicles mitigates severe spinal cord injury

A Fang, Y Wang, N Guan, Y Zuo, L Lin, B Guo… - nature …, 2023 - nature.com
The transplantation of mesenchymal stem cells-derived secretome, particularly extracellular
vesicles is a promising therapy to suppress spinal cord injury-triggered neuroinflammation …

[HTML][HTML] Advancing herbal medicine: enhancing product quality and safety through robust quality control practices

H Wang, Y Chen, L Wang, Q Liu, S Yang… - Frontiers in …, 2023 - frontiersin.org
This manuscript provides an in-depth review of the significance of quality control in herbal
medication products, focusing on its role in maintaining efficiency and safety. With a …

[HTML][HTML] Production and utility of extracellular vesicles with 3D culture methods

M Casajuana Ester, RM Day - Pharmaceutics, 2023 - mdpi.com
In recent years, extracellular vesicles (EVs) have emerged as promising biomarkers, cell-
free therapeutic agents, and drug delivery carriers. Despite their great clinical potential, poor …