[HTML][HTML] Global epidemiology of cirrhosis—aetiology, trends and predictions

DQ Huang, NA Terrault, F Tacke, LL Gluud… - Nature reviews …, 2023 - nature.com
Cirrhosis is an important cause of morbidity and mortality in people with chronic liver
disease worldwide. In 2019, cirrhosis was associated with 2.4% of global deaths. Owing to …

Global prevalence of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in the overweight and obese population: a systematic review and meta …

J Quek, KE Chan, ZY Wong, C Tan, B Tan… - The lancet …, 2023 - thelancet.com
Background The global burden of non-alcoholic fatty liver disease (NAFLD) parallels the
increase in obesity rates across the world. Although overweight and obesity status are …

[PDF][PDF] Changing global epidemiology of liver cancer from 2010 to 2019: NASH is the fastest growing cause of liver cancer

DQ Huang, AG Singal, Y Kono, DJH Tan, HB El-Serag… - Cell metabolism, 2022 - cell.com
Liver cancer epidemiology is changing due to increasing alcohol consumption, rising
prevalence of obesity, and advances in hepatitis B virus (HBV) and hepatitis C virus (HCV) …

AASLD practice guidance on prevention, diagnosis, and treatment of hepatocellular carcinoma

AG Singal, JM Llovet, M Yarchoan, N Mehta… - Hepatology, 2023 - journals.lww.com
This guidance document provides an updated approach to the prevention, diagnosis, and
treatment of hepatocellular carcinoma (HCC). The prior American Association for the Study …

Nonalcoholic steatohepatitis-related hepatocellular carcinoma: pathogenesis and treatment

JM Llovet, CE Willoughby, AG Singal… - Nature reviews …, 2023 - nature.com
Nonalcoholic fatty liver disease (NAFLD), including its more severe manifestation,
nonalcoholic steatohepatitis (NASH), has a global prevalence of 20–25% and is a major …

Global epidemiology and genetics of hepatocellular carcinoma

MR Toh, EYT Wong, SH Wong, AWT Ng, LH Loo… - Gastroenterology, 2023 - Elsevier
Hepatocellular carcinoma (HCC) is one of the leading cancers worldwide. Classically, HCC
develops in genetically susceptible individuals who are exposed to risk factors, especially in …

Recompensation in cirrhosis: unravelling the evolving natural history of nonalcoholic fatty liver disease

G Feng, L Valenti, VWS Wong, YM Fouad… - Nature Reviews …, 2023 - nature.com
Recompensation has gained increasing attention in the field of cirrhosis, particularly in
chronic liver disease with a definite aetiology. The current global prevalence of obesity and …

Comparative burden of metabolic dysfunction in lean NAFLD vs non-lean NAFLD-a systematic review and meta-analysis

A Tang, CH Ng, PH Phang, KE Chan, YH Chin… - Clinical …, 2023 - Elsevier
Background & Aims Nonalcoholic fatty liver disease (NAFLD) is traditionally associated with
obesity. However, there is a subtype of NAFLD, namely NAFLD in lean, that occurs without …

Global burden of liver cancer in males and females: changing etiological basis and the growing contribution of NASH

DJH Tan, VW Setiawan, CH Ng, WH Lim… - Hepatology, 2023 - journals.lww.com
Global burden of liver cancer in males and females: Changing... : Hepatology Global burden of
liver cancer in males and females: Changing etiological basis and the growing contribution of …

[HTML][HTML] Type 2 diabetes, hepatic decompensation, and hepatocellular carcinoma in patients with non-alcoholic fatty liver disease: an individual participant-level data …

DQ Huang, N Noureddin, V Ajmera… - The Lancet …, 2023 - thelancet.com
Background Data are scarce regarding the development of hepatic decompensation in
patients with non-alcoholic fatty liver disease (NAFLD) with and without type 2 diabetes. We …