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Bacterial biofilms can cause widespread infection. In addition to causing urinary tract
infections and pulmonary infections in patients with cystic fibrosis, biofilms can help …

Background The addition of vancomycin to beta-lactam prophylaxis in arthroplasty may
reduce surgical-site infections; however, the efficacy and safety are unclear. Methods In this …

Orthopedic implants account for 99% of orthopedic surgeries, however, orthopedic implant-
related infection is one of the most serious complications owing to the potential for limb …

Over the last several decades, periprosthetic joint infection has been increasing in incidence
and is occurring in more complex patients. While there have been advances in both surgical …

Implants are widely used in orthopedic surgery and are gaining attention of late. However,
their use is restricted by implant-associated infections (IAI), which represent one of the most …

Titanium (Ti) was an excellent medical metal material, but the lack of good antibacterial
activity confined its further practical application. To solve this dilemma, a coating containing …

Successful joint replacement is a life-enhancing procedure with significant growth in the past
decade. Prosthetic joint infection occurs rarely; it is a biofilm-based infection that is poorly …

Background Next-generation sequencing (NGS) is increasingly used for periprosthetic joint
infection (PJI) diagnosis, but its clinical utility is poorly defined. Shotgun metagenomic …

Identification of the causative organism (s) in periprosthetic joint infection (PJI) is a
challenging task. The shortcomings of traditional cultures have been emphasized in recent …