The developing fetus requires substantial amounts of fatty acids to support rapid cellular
growth and activity. Although the fatty acid composition delivered to the fetus is largely …

BACKGROUND While oocyte IVM is practiced sporadically it has not achieved widespread
clinical practice globally. However, recently there have been some seminal advances in our …

It is well established that cAMP signaling is an important regulator of the oocyte meiotic cell
cycle. Conversely, the function of cGMP during oocyte maturation is less clear. Herein, we …

In vitro maturation (IVM) of human immature oocytes has been shown to be a viable option
for patients at risk of ovarian hyperstimulation syndrome (OHSS), those seeking urgent …

Mammalian oocytes reach prophase of first meiosis around the time of birth, and remain at
this stage for months or years, depending on the species. Only after puberty will the fully …

In vitro maturation (IVM) of human immature oocytes has been offered to women who are at
risk of developing ovarian hyperstimulation syndrome (OHSS) caused by gonadotropin …

Mammalian oocytes are arrested at prophase I until puberty when luteinizing hormone (LH)
induces resumption of meiosis of follicle-enclosed oocytes. Resumption of meiosis is tightly …

In males, Mullerian inhibiting substance (MIS) mRNA was first detected on the medial aspect
of the urogenital ridge early on the morning of day 13 of gestation before testicular …

Mucification (or expansion) of the cumulus cells surrounding the oocyte is thought to depend
on the direct action of gonadotropins in stimulating production and deposition of hyaluronic …

Mullerian inhibiting substance (MIS) in the adult rat ovary can be detected by
immunohistochemistry in the granulosa cells of growing preantral follicles and in the …