Metabolomics and isotope tracing
Great strides have been made over the past decade toward comprehensive study of
metabolism. Mass spectrometry (MS) has played a central role by enabling measurement of …
metabolism. Mass spectrometry (MS) has played a central role by enabling measurement of …
Bacterial metabolism and antibiotic efficacy
Antibiotics target energy-consuming processes. As such, perturbations to bacterial metabolic
homeostasis are significant consequences of treatment. Here, we describe three postulates …
homeostasis are significant consequences of treatment. Here, we describe three postulates …
Metabolic cooperation and spatiotemporal niche partitioning in a kefir microbial community
Microbial communities often undergo intricate compositional changes yet also maintain
stable coexistence of diverse species. The mechanisms underlying long-term coexistence …
stable coexistence of diverse species. The mechanisms underlying long-term coexistence …
L-arginine modulates T cell metabolism and enhances survival and anti-tumor activity
Metabolic activity is intimately linked to T cell fate and function. Using high-resolution mass
spectrometry, we generated dynamic metabolome and proteome profiles of human primary …
spectrometry, we generated dynamic metabolome and proteome profiles of human primary …
Toward merging untargeted and targeted methods in mass spectrometry-based metabolomics and lipidomics
Advances in mass spectrometry (MS) and data processing have led to discoveries in
regulation of cellular metabolism by using metabolomics and lipidomics approaches. 1, 2 …
regulation of cellular metabolism by using metabolomics and lipidomics approaches. 1, 2 …
Arginine reprograms metabolism in liver cancer via RBM39
D Mossmann, C Müller, S Park, B Ryback, M Colombi… - Cell, 2023 - cell.com
Metabolic reprogramming is a hallmark of cancer. However, mechanisms underlying
metabolic reprogramming and how altered metabolism in turn enhances tumorigenicity are …
metabolic reprogramming and how altered metabolism in turn enhances tumorigenicity are …
Metabolomics: a primer
X Liu, JW Locasale - Trends in biochemical sciences, 2017 - cell.com
Metabolomics generates a profile of small molecules that are derived from cellular
metabolism and can directly reflect the outcome of complex networks of biochemical …
metabolism and can directly reflect the outcome of complex networks of biochemical …
[HTML][HTML] Metabolic pathways in T cell activation and lineage differentiation
L Almeida, M Lochner, L Berod, T Sparwasser - Seminars in immunology, 2016 - Elsevier
Recent advances in the field of immunometabolism support the concept that fundamental
processes in T cell biology, such as TCR-mediated activation and T helper lineage …
processes in T cell biology, such as TCR-mediated activation and T helper lineage …
Metabolite measurement: pitfalls to avoid and practices to follow
Metabolites are the small biological molecules involved in energy conversion and
biosynthesis. Studying metabolism is inherently challenging due to metabolites' reactivity …
biosynthesis. Studying metabolism is inherently challenging due to metabolites' reactivity …
Reduction of translating ribosomes enables Escherichia coli to maintain elongation rates during slow growth
X Dai, M Zhu, M Warren, R Balakrishnan… - Nature …, 2016 - nature.com
Bacteria growing under different conditions experience a broad range of demand on the rate
of protein synthesis, which profoundly affects cellular resource allocation. During fast growth …
of protein synthesis, which profoundly affects cellular resource allocation. During fast growth …