[HTML][HTML] Dysfunctional vascular endothelium as a driver of atherosclerosis: emerging insights into pathogenesis and treatment
Atherosclerosis, the chronic accumulation of cholesterol-rich plaque within arteries, is
associated with a broad spectrum of cardiovascular diseases including myocardial …
associated with a broad spectrum of cardiovascular diseases including myocardial …
Innate immunity in vertebrates: an overview
M Riera Romo, D Pérez‐Martínez… - …, 2016 - Wiley Online Library
Innate immunity is a semi‐specific and widely distributed form of immunity, which represents
the first line of defence against pathogens. This type of immunity is critical to maintain …
the first line of defence against pathogens. This type of immunity is critical to maintain …
[HTML][HTML] Cytokines in atherosclerosis: Key players in all stages of disease and promising therapeutic targets
Atherosclerosis, a chronic inflammatory disorder of the arteries, is responsible for most
deaths in westernized societies with numbers increasing at a marked rate in developing …
deaths in westernized societies with numbers increasing at a marked rate in developing …
[HTML][HTML] Lycopene: a natural arsenal in the war against oxidative stress and cardiovascular diseases
Lycopene is a bioactive red pigment found in plants, especially in red fruits and vegetables,
including tomato, pink guava, papaya, pink grapefruit, and watermelon. Several research …
including tomato, pink guava, papaya, pink grapefruit, and watermelon. Several research …
Anticytokine agents: targeting interleukin signaling pathways for the treatment of atherothrombosis
PM Ridker - Circulation research, 2019 - Am Heart Assoc
The recognition that atherosclerosis is a complex chronic inflammatory disorder mediated
through both adaptive and innate immunity has led to the hypothesis that anticytokine …
through both adaptive and innate immunity has led to the hypothesis that anticytokine …
Tumor necrosis factor-α signaling in macrophages
N Parameswaran, S Patial - Critical Reviews™ in Eukaryotic …, 2010 - dl.begellhouse.com
Tumor necrosis factor-α (TNFα) was cloned over 2 decades ago and its identification in part
led to the discovery of a super family of tumor necrosis factors (TNFs) and their receptors …
led to the discovery of a super family of tumor necrosis factors (TNFs) and their receptors …
[HTML][HTML] Alternatively activated macrophages determine repair of the infarcted adult murine heart
M Shiraishi, Y Shintani, Y Shintani… - The Journal of …, 2016 - Am Soc Clin Investig
Alternatively activated (also known as M2) macrophages are involved in the repair of various
types of organs. However, the contribution of M2 macrophages to cardiac repair after …
types of organs. However, the contribution of M2 macrophages to cardiac repair after …
[HTML][HTML] Natural killer cells: In health and disease
A Mandal, C Viswanathan - Hematology/oncology and stem cell therapy, 2015 - Elsevier
Natural killer (NK) cells constitute our bodies' frontline defense system, guarding against
tumors and launching attacks against infections. The activities of NK cells are regulated by …
tumors and launching attacks against infections. The activities of NK cells are regulated by …
Molecular biology of atherosclerosis
PN Hopkins - Physiological reviews, 2013 - journals.physiology.org
At least 468 individual genes have been manipulated by molecular methods to study their
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …
Alternative activation of macrophages: an immunologic functional perspective
FO Martinez, L Helming, S Gordon - Annual review of …, 2009 - annualreviews.org
Macrophages are innate immune cells with well-established roles in the primary response to
pathogens, but also in tissue homeostasis, coordination of the adaptive immune response …
pathogens, but also in tissue homeostasis, coordination of the adaptive immune response …