Abstract Three-dimensional (3D) stem cell culture systems have attracted considerable
attention as a way to better mimic the complex interactions between individual cells and the …

Biofabricated tissues have found numerous applications in tissue engineering and
regenerative medicine in addition to the promotion of disease modeling and drug …

Tissue engineering (TE) is a highly interdisciplinary research field driven by the goal to
restore, replace, or regenerate defective tissues. Throughout more than two decades of …

Bottom‐up tissue engineering is a promising approach for designing modular biomimetic
structures that aim to recapitulate the intricate hierarchy and biofunctionality of native human …

A number of challenges in skin grafting for wound healing have drawn researchers to focus
on skin tissue engineering as an alternative solution. The core idea of tissue engineering is …

Background An impressive percentage of biomedical advances were achieved through
animal research and cell culture investigations. For drug testing and disease researches …

Three-dimensional (3D) culture of multicellular spheroids, offering a desirable biomimetic
microenvironment, is appropriate for recapitulating tissue cellular adhesive complexity and …

Biological self-assembly is crucial in the processes of development, tissue regeneration, and
maturation of bioprinted tissue-engineered constructions. The cell aggregates—spheroids …

One of the most arduous challenges in tissue engineering is neovascularization, without
which there is a lack of nutrients delivered to a target tissue. Angiogenesis should be …

Mechanics are intrinsic properties which appears throughout the formation, development,
and aging processes of biological systems. Mechanics have been shown to play important …