Critical determinants of cytokine storm and type I interferon response in COVID-19 pathogenesis
S Ramasamy, S Subbian - Clinical microbiology reviews, 2021 - Am Soc Microbiol
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus
disease 2019 (COVID-19), a rapidly evolving pandemic worldwide with at least 68 million …
disease 2019 (COVID-19), a rapidly evolving pandemic worldwide with at least 68 million …
[HTML][HTML] Cholesterol-induced toxicity: An integrated view of the role of cholesterol in multiple diseases
Y Song, J Liu, K Zhao, L Gao, J Zhao - Cell metabolism, 2021 - cell.com
High levels of cholesterol are generally considered to be associated with atherosclerosis. In
the past two decades, however, a number of studies have shown that excess cholesterol …
the past two decades, however, a number of studies have shown that excess cholesterol …
[HTML][HTML] Low HDL and high triglycerides predict COVID-19 severity
Lipids are indispensable in the SARS-CoV-2 infection process. The clinical significance of
plasma lipid profile during COVID-19 has not been rigorously evaluated. We aim to …
plasma lipid profile during COVID-19 has not been rigorously evaluated. We aim to …
Cholesterol, lipoproteins, and COVID-19: Basic concepts and clinical applications
Cholesterol is being recognized as a molecule involved in regulating the entry of the SARS-
CoV-2 virus into the host cell. However, the data about the possible role of cholesterol …
CoV-2 virus into the host cell. However, the data about the possible role of cholesterol …
Dissecting lipid metabolism alterations in SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the COVID-
19 pandemic that has infected over a hundred million people globally. There have been …
19 pandemic that has infected over a hundred million people globally. There have been …
[HTML][HTML] Modulation of macrophage immunometabolism: A new approach to fight infections
T Gauthier, W Chen - Frontiers in Immunology, 2022 - frontiersin.org
Macrophages are essential innate immune cells that contribute to host defense during
infection. An important feature of macrophages is their ability to respond to extracellular cues …
infection. An important feature of macrophages is their ability to respond to extracellular cues …
[HTML][HTML] Coronavirus infection and cholesterol metabolism
J Dai, H Wang, Y Liao, L Tan, Y Sun, C Song… - Frontiers in …, 2022 - frontiersin.org
Host cholesterol metabolism remodeling is significantly associated with the spread of human
pathogenic coronaviruses, suggesting virus-host relationships could be affected by …
pathogenic coronaviruses, suggesting virus-host relationships could be affected by …
[HTML][HTML] Metabolic alterations upon SARS-CoV-2 infection and potential therapeutic targets against coronavirus infection
Abstract The coronavirus disease 2019 (COVID-19) caused by coronavirus SARS-CoV-2
infection has become a global pandemic due to the high viral transmissibility and …
infection has become a global pandemic due to the high viral transmissibility and …
A single-nucleus transcriptomic atlas of primate liver aging uncovers the pro-senescence role of SREBP2 in hepatocytes
S Yang, C Liu, M Jiang, X Liu, L Geng, Y Zhang… - Protein & …, 2024 - academic.oup.com
Aging increases the risk of liver diseases and systemic susceptibility to aging-related
diseases. However, cell type-specific changes and the underlying mechanism of liver aging …
diseases. However, cell type-specific changes and the underlying mechanism of liver aging …
[HTML][HTML] Lipoprotein concentrations over time in the intensive care unit COVID-19 patients: Results from the ApoCOVID study
S Tanaka, C De Tymowski, M Assadi, N Zappella… - PloS one, 2020 - journals.plos.org
Introduction Severe acute respiratory syndrome coronavirus2 has caused a global
pandemic of coronavirus disease 2019 (COVID-19). High-density lipoproteins (HDLs) …
pandemic of coronavirus disease 2019 (COVID-19). High-density lipoproteins (HDLs) …