Cutaneous melanoma (CM) is a multifactorial disease whose treatment still presents
challenges: the rapid progression to advanced CM, which leads to frequent recurrences …

Chemerin [RARRES2 [retinoic acid receptor responder 2], TIG2 [tazarotene induced gene 2
(TIG2)]] is a multifunctional cytokine initially described in skin cultures upon exposure to the …

Background: Melanoma is highly immunogenic and therefore suitable for immunotherapy,
but the efficacy is limited by response rate. In several types of tumor, tumor mutation burden …

Background Skin self-examinations supplemented with mobile teledermoscopy might
improve early detection of skin cancers compared with naked-eye skin self-examinations …

Importance Two pathways have been hypothesized for the development of cutaneous
melanoma: one typically affects the head and neck, a site with chronic sun damage, and the …

Malignant melanoma (MM) is the most fatal skin cancer, whose incidence has critically
increased in the last decades. Recent molecular therapies are giving excellent results in the …

In this study we evaluated the anticancer activity against malignant melanoma (MM) of four
different vanadium species: the inorganic anion vanadate (V)(indicated with VN), and three …

Cutaneous melanoma is an aggressive tumor; its incidence has been reported to increase
fast in the past decades. Melanoma is a heterogeneous tumor, with most patients harboring …

Simple Summary Tumor immune evasion is mediated in large part by the inhibition of anti-
tumor T cell responses. Both the induction of tumor antigen-specific T cells and the activation …

Background Immunotherapies targeting programmed cell death-1 (PD-1) and its ligands
have improved clinical outcomes for advanced melanoma. However, many tumors exhibit …