Lung cancer immunotherapy: progress, pitfalls, and promises

A Lahiri, A Maji, PD Potdar, N Singh, P Parikh, B Bisht… - Molecular cancer, 2023 - Springer
Lung cancer is the primary cause of mortality in the United States and around the globe.
Therapeutic options for lung cancer treatment include surgery, radiation therapy …

Impact of proton pump inhibitors and histamine-2-receptor antagonists on non-small cell lung cancer immunotherapy: a systematic review and meta-analysis

A Rizzo, A Cusmai, F Giovannelli, S Acquafredda… - Cancers, 2022 - mdpi.com
Simple Summary The current meta-analysis highlighted that proton pump inhibitors (PPIs)
and histamine-2-receptor antagonists (H2RAs) could impact immune checkpoint inhibitors …

PD‐1/PD‐L1 blockade therapy in advanced non‐small‐cell lung cancer: current status and future directions

L Xia, Y Liu, Y Wang - The oncologist, 2019 - academic.oup.com
The use of immune checkpoint inhibitors (ICIs) has become one of the most promising
approaches in the field of cancer therapy. Unlike the current therapies that target tumor cells …

Immune checkpoint inhibitors in non-small cell lung cancer: progress, challenges, and prospects

S Tang, C Qin, H Hu, T Liu, Y He, H Guo, H Yan… - Cells, 2022 - mdpi.com
Non-small cell lung cancer is one of the most common types of malignances worldwide and
the main cause of cancer-related deaths. Current treatment for NSCLC is based on surgical …

The prognostic landscape of tumor-infiltrating immune cell and immunomodulators in lung cancer

X Liu, S Wu, Y Yang, M Zhao, G Zhu, Z Hou - Biomedicine & …, 2017 - Elsevier
Tumor-infiltrating immune cells are closely associated with clinical outcome. However,
immunohistochemistry-based analysis of tumor infiltrates can be misleading as the …

Membrane active peptides and their biophysical characterization

FG Avci, B Sariyar Akbulut, E Ozkirimli - Biomolecules, 2018 - mdpi.com
In the last 20 years, an increasing number of studies have been reported on membrane
active peptides. These peptides exert their biological activity by interacting with the cell …

Biomarker-targeted therapies in non–small cell lung cancer: current status and perspectives

H Guo, J Zhang, C Qin, H Yan, T Liu, H Hu, S Tang… - Cells, 2022 - mdpi.com
Non-small-cell lung cancer (NSCLC) is one of the most common malignancies and the
leading causes of cancer-related death worldwide. Despite many therapeutic advances in …

[HTML][HTML] What's new in SCLC? A review

B Oronsky, TR Reid, A Oronsky, CA Carter - Neoplasia, 2017 - Elsevier
A few years ago the answer to the question in the title of this review would have
been,“unfortunately not much” or even “nothing”, likely eliciting knowing nods of agreement …

BTK has potential to be a prognostic factor for lung adenocarcinoma and an indicator for tumor microenvironment remodeling: a study based on TCGA data mining

KW Bi, XG Wei, XX Qin, B Li - Frontiers in oncology, 2020 - frontiersin.org
Tumor microenvironment (TME) plays a crucial role in the initiation and progression of lung
adenocarcinoma (LUAD); however, there is still a challenge in understanding the dynamic …

Soluble programmed cell death ligand 1 as a novel biomarker for nivolumab therapy for non–small-cell lung cancer

Y Okuma, H Wakui, H Utsumi, Y Sagawa, Y Hosomi… - Clinical lung cancer, 2018 - Elsevier
Background Biomarkers for predicting the effect of anti–programmed cell death 1 (PD-1)
monoclonal antibody against non–small-cell lung cancer (NSCLC) are urgently required …