Promises and challenges of big data computing in health sciences

T Huang, L Lan, X Fang, P An, J Min, F Wang - Big Data Research, 2015 - Elsevier
With the development of smart devices and cloud computing, more and more public health
data can be collected from various sources and can be analyzed in an unprecedented way …

Plant ionomics: from elemental profiling to environmental adaptation

XY Huang, DE Salt - Molecular plant, 2016 - cell.com
Ionomics is a high-throughput elemental profiling approach to study the molecular
mechanistic basis underlying mineral nutrient and trace element composition (also known …

The antagonistic effect of selenium on cadmium-induced apoptosis via PPAR-γ/PI3K/Akt pathway in chicken pancreas

X Jin, T Jia, R Liu, S Xu - Journal of Hazardous Materials, 2018 - Elsevier
The animal experiment was preformed to investigate the roles of PPAR-γ/PI3K/Akt pathway
in apoptosis triggered by cadmium (Cd) and in the antagonistic effects of selenium (Se) on …

Genetic differences among ethnic groups

T Huang, Y Shu, YD Cai - BMC genomics, 2015 - Springer
Background Many differences between different ethnic groups have been observed, such as
skin color, eye color, height, susceptibility to some diseases, and response to certain drugs …

Association of serum zinc levels in overweight and obesity

MJ Rios-Lugo, C Madrigal-Arellano… - Biological trace element …, 2020 - Springer
Low levels of zinc (Zn) have adverse effects on physiological and metabolic functions in
humans, especially in processes linked with obesity. In this work, serum Zn levels and their …

Relationship between the concentrations of heavy metals and bioelements in aging men with metabolic syndrome

I Rotter, D Kosik-Bogacka, B Dołęgowska… - International journal of …, 2015 - mdpi.com
Heavy metals may exacerbate metabolic syndrome (MS) but abnormal serum
concentrations of bioelements may also co-exist with MS. The primary aim of the study was …

Manganese transporter Slc39a14 deficiency revealed its key role in maintaining manganese homeostasis in mice

Y Xin, H Gao, J Wang, Y Qiang, MU Imam, Y Li, J Wang… - Cell discovery, 2017 - nature.com
SLC39A14 (also known as ZIP14), a member of the SLC39A transmembrane metal
transporter family, has been reported to mediate the cellular uptake of iron and zinc …

Macro and trace elements signature of periodontitis in saliva: A systematic review with quality assessment of ionomics studies

G Baima, G Iaderosa, M Corana… - Journal of …, 2022 - Wiley Online Library
Objectives The present systematic review examined the available evidence on distinctive
salivary ion profile in periodontitis compared to periodontal health and provided a qualitative …

Elemental metabolomics and pregnancy outcomes

DR McKeating, JJ Fisher, AV Perkins - Nutrients, 2019 - mdpi.com
Trace elements are important for human health and development. The body requires
specific micronutrients to function, with aberrant changes associated with a variety of …

Associations of serum and urinary magnesium with the pre-diabetes, diabetes and diabetic complications in the Chinese Northeast population

J Xu, W Xu, H Yao, W Sun, Q Zhou, L Cai - PLoS One, 2013 - journals.plos.org
The effect of magnesium (Mg) deficiency on the prevalence of diabetes and diabetic
complications has received a great attention. The present study investigated the association …