The role of IgLON cell adhesion molecules in neurodegenerative diseases

M Salluzzo, C Vianello, S Abdullatef, R Rimondini… - Genes, 2023 - mdpi.com
In the brain, cell adhesion molecules (CAMs) are critical for neurite outgrowth, axonal
fasciculation, neuronal survival and migration, and synapse formation and maintenance …

Mendelian randomization studies of depression: evidence, opportunities, and challenges

W Ma, L Zhang, J Ma, F Yu, Y Hou, X Feng… - Annals of General …, 2023 - Springer
Background Major depressive disorder (MDD) poses a significant social and economic
burden worldwide. Identifying exposures, risk factors, and biological mechanisms that are …

Genetic insights into obesity and brain: combine Mendelian randomization study and gene expression analysis

L Chen, S Zhao, Y Wang, X Niu, B Zhang, X Li, D Peng - Brain Sciences, 2023 - mdpi.com
As a major public-health concern, obesity is imposing an increasing social burden around
the world. The link between obesity and brain-health problems has been reported, but …

Risk cycling in diabetes and autism spectrum disorder: a bidirectional Mendelian randomization study

Y Yu, X Yang, G Hu, K Tong, J Wu, R Yu - Frontiers in Endocrinology, 2024 - frontiersin.org
Objective The relationship between diabetes mellitus (DM) and autism spectrum disorder
(ASD) remains controversial. This study aimed to analyze the causal relationship between …

The Risk Genes for Neuropsychiatric Disorders negr1 and opcml Are Expressed throughout Zebrafish Brain Development

J Habicher, I Sanvido, A Bühler, S Sartori, G Piccoli… - Genes, 2024 - mdpi.com
The immunoglobulin LAMP/OBCAM/NTM (IgLON) family of cell adhesion molecules
comprises five members known for their involvement in establishing neural circuit …

The importance of the human microbiome for mental health

A Refisch, M Walter - Der Nervenarzt, 2023 - europepmc.org
Abstract Die Zusammensetzung des Mikrobioms ist bei vielen häufigen psychiatrischen
Erkrankungen verändert. Präklinische Studien haben wichtige Mechanismen aufgedeckt …

[HTML][HTML] 孟德尔随机化研究在孤独症谱系障碍中的研究进展

胡云扬, 田耕畅, 刘蒙, 汪鸿 - Chinese Journal of Contemporary …, 2024 - ncbi.nlm.nih.gov
孤独症谱系障碍( autism spectrum disorder, ASD) 是一种婴幼儿期起病的广泛神经发育障碍性
疾病。 孟德尔随机化( Mendelian randomization, MR) 是一种推导暴露与结局之间因果关系的 …

Die Bedeutung des humanen Mikrobioms für die psychische Gesundheit

A Refisch, M Walter - Der Nervenarzt, 2023 - Springer
Zusammenfassung Die Zusammensetzung des Mikrobioms ist bei vielen häufigen
psychiatrischen Erkrankungen verändert. Präklinische Studien haben wichtige …

Генетическая коморбидность депрессии и соматических заболеваний: обоснование дизайна изучения популяционной когорты с использованием полигенных …

АО Кибитов, ГЭ Мазо, ЕД Касьянов… - …, 2024 - journalpsychiatry.com
Аннотация Обоснование: депрессия широко распространена в популяции и является
одной из ведущих причин инвалидизации, снижения продолжительности жизни и …