Restricting the intake of calories has been practiced as a method for increasing both the
length and quality of life for over 500years. Experimental work confirming the success of this …

Aging is characterized by an increasing morbidity and functional decline that eventually
results in the death of an organism. Aging is the largest risk factor for numerous human …

ABSTRACT A common, long‐held belief is that metabolic rate drives the rates of various
biological, ecological and evolutionary processes. Although this metabolic pacemaker view …

Most research on mechanisms of aging is being conducted in a very limited number of
classical model species, ie, laboratory mouse (Mus musculus), rat (Rattus norvegicus …

Research programmes on oxidative stress and hormesis are wide ranging. Biomedical and
toxicological sciences have traditionally centralised such research, but in the last years we …

The Flexible Phenotype attempts a true synthesis of physiology, behaviour, and ecology by
developing an empirical argument that describes the intimate connections between …

The role of energy in ecological processes has hitherto been considered primarily from the
standpoint that energy supply is limited. That is, traditional resource‐based ecological and …

The idea that resources are limited and animals can maximise fitness by trading costly
activities off against one another forms the basis of life-history theory. Although investment in …

Consistent patterns of positive selection in functionally similar genes can suggest a common
selective pressure across a group of species. We use alignments of orthologous protein …

The idea that oxidative stress may underpin life history trade‐offs has become extremely
popular. However, experimental support for the concept has proved equivocal. It has …