A comprehensive overview of β-carbolines and its derivatives as anticancer agents

B Luo, X Song - European Journal of Medicinal Chemistry, 2021 - Elsevier
Abstract β-Carboline alkaloids are a family of natural and synthetic products with structural
diversity and outstanding antitumor activities. This review summarizes research …

A Review of Pharmacological and Toxicological Effects of Sophora tonkinensis with Bioinformatics Prediction

SN Zhang, XZ Li, LY Tan, KY Zhu - The American Journal of …, 2021 - World Scientific
Sophora tonkinensis Gagnep.(ST)(Fabaceae) is distributed chiefly in south-central and
southeast China and Vietnam. In traditional Chinese medicine theory, the root and rhizome …

Identification, formation, and occurrence of perlolyrine: A β-carboline alkaloid with a furan moiety in foods

T Herraiz, A Peña, A Salgado - Journal of Agricultural and Food …, 2023 - ACS Publications
β-Carbolines are naturally occurring bioactive alkaloids found in foods and in vivo. This
research reports the identification, characterization, mechanism of formation, and …

Quinolizidine alkaloids from Sophora tonkinensis and their anti-inflammatory activities

LJ He, JS Liu, D Luo, YR Zheng, YB Zhang, GC Wang… - Fitoterapia, 2019 - Elsevier
Two new quinolizidine-based alkaloids (2 and 12), along with ten known ones (1, 3–11)
were isolated from the roots of S. tonkinensis. Their structures were determined by …

Quinolizidine alkaloids from Sophora alopecuroides with anti-inflammatory and anti-tumor properties

JC Li, WF Dai, D Liu, ZJ Zhang, MY Jiang, KR Rao… - Bioorganic …, 2021 - Elsevier
Abstract Forty-three quinolizidine alkaloids (1–43), including twelve new matrine-type ones,
sophalodes A–L (1–7, 17, 19 and 28–30), were isolated from the seeds of Sophora …

[HTML][HTML] Preparative Purification of Total Flavonoids from Sophora tonkinensis Gagnep. by Macroporous Resin Column Chromatography and Comparative Analysis of …

M Hou, W Hu, Z Xiu, A Jiang, L Men, K Hao, X Sun… - Molecules, 2019 - mdpi.com
For the full development and utilization of Sophora tonkinensis Gagnep., this study was
primarily intended to established a simple and efficient approach for the preparative …

Water-soluble matrine-type alkaloids with potential anti-neuroinflammatory activities from the seeds of Sophora alopecuroides

D Luo, Q Lin, JL Tan, HY Zhao, X Feng, NH Chen… - Bioorganic …, 2021 - Elsevier
A phytochemical investigation on the alkaloids from water-soluble part of Sophora
alopecuroides led to obtain forty matrine-type alkaloids (1–40) including eighteen new ones …

[HTML][HTML] Five matrine-type alkaloids from Sophora tonkinensis

Q Tang, D Luo, DC Lin, WZ Wang, CJ Li… - Journal of natural …, 2021 - Springer
Abstract Five matrine-type alkaloids (1‒5) including two new compounds (1 and 3) and a
new natural product (2) were isolated from the roots of Sophora tonkinesis. Their structures …

Matrine‐Type Alkaloids from the Seeds of Sophora alopecuroides and Their Potential Anti‐inflammatory Activities

JC Li, WF Dai, XQ Zhou, KR Rao… - Chemistry & …, 2021 - Wiley Online Library
Three new matrine‐type alkaloids, 8β‐hydroxyoxysophoridine (1), 9β‐hydroxysophoridine
(2), 9β‐hydroxyisosophocarpine (3), together with one known analog, 11, 12 …

Chemical Constituents from the Roots and Rhizomes of Sophora tonkinensis and Their Effects on Proprotein Convertase Substilisin/Kexin Type 9 Expression

P Pel, HS Chae, P Nhoek, YM Kim, CY An, H Yoo… - ACS …, 2022 - ACS Publications
This study was conducted to further investigate bioactive molecules from Sophora
tonkinensis that can inhibit proprotein convertase substilisin/kexin type 9 (PCSK9) …