Cancer is a major health issue worldwide, and the global burden of cancer is expected to
increase in the coming years. Whereas the limited success with current therapies has driven …

Breast cancer (BC) is mostly observed in women and is responsible for huge mortality in
women subjects globally. Due to the continued development of drug resistance and other …

High recurrence and metastasis of triple-negative breast cancer (TNBC) after operation is a
leading cause of breast cancer related death. The pre-metastatic niche (PMN) is an …

Human malignancies are one of the major health-related issues though out the world and
anticipated to rise in the future. The development of novel drugs/agents requires a huge …

Integrins are cell adhesion receptors, which are typically transmembrane glycoproteins that
connect to the extracellular matrix (ECM). The function of integrins regulated by biochemical …

Background The diagnosis of cancer is strongly associated with the risk of mental disorders
even in patients with no previous history of mental disorders. Accumulating data suggest that …

Targeted therapies and immunotherapy have brought substantial benefits to patients with
melanoma. However, brain metastases remain the biggest threat to the survival and quality …

Staphylococcus aureus has increasingly attracted global attention as a major opportunistic
human pathogen owing to the emergence of biofilms (BFs) and persisters that are known to …

As one of the hallmarks of cancer, metabolic reprogramming leads to cancer progression,
and targeting glycolytic enzymes could be useful strategies for cancer therapy. By screening …

The dopamine D2 receptor (D2R) family is upregulated in many cancers and tied to
stemness. Reduced cancer risk has been correlated with disorders such as schizophrenia …